Senior Modelling and Simulation Expert

2 weeks ago

London, Greater London, United Kingdom Biopretium Full time
Job Title: Director, Modelling & Simulation

Location: Remote in the UK. Occasional need to be in the office in the North East or Berkshire.

The Opportunity

Biopretium has been retained by a drug development and manufacturing business providing integrated programs and tailored services across the entire development pathway. They partner with pharmaceutical and biotech companies to accelerate their drug development processes and ultimately get treatments to patients more quickly.

With more than 1200 employees globally across all business units, with facilities across the UK and US, this company are well established experts in their fields and experiencing consistent growth. This particular opportunity has arisen as a result of that growth.

The Role

Due to growth and expansion, we are looking for an experienced professional to join the team as a Senior/Director, Modelling and Simulation. This role can be based anywhere in the UK, although occasionally you may need to attend team meetings in Berkshire or Nottingham.

As a key member of the Scientific Consulting team, you will provide leadership for the Modelling and Simulation (M&S) team, managing resources to deliver customer projects meeting time, budget and quality criteria.

You will also drive customer adoption of M&S activities, working with the commercial team to promote their scientific capabilities and secure new standalone and integrated programs of work.

Assessing and adopting new M&S applications to increase the breadth of their offering to drive growth. Performing hands-on modelling and simulation (M&S) scientific support and input throughout the project lifecycle (design, planning, delivery and reporting) to ensure client's study objectives are achieved.

Main tasks and responsibilities:

  • Manage M&S team, ensuring availability of sufficient resources and capabilities for delivery of project work to agreed timelines and budget.
  • As leader of the Modelling & Simulation function, and a prominent member of the wider Scientific Consulting team, you will work together to prioritise activities to achieve agreed annual measurables.
  • Work with the commercial and marketing team to promote service offerings in the marketplace via appropriate channels and materials, including website, factsheet, scientific publications and conference attendance
  • Provide scientific support to effectively communicate the company's modelling capabilities and offerings in customer discussions
  • Perform hands-on PBPK M&S activities to deliver customer projects where necessary
  • Produce high quality reports which clearly present and summarise M&S project findings

The Candidate

The successful applicant will be degree qualified, ideally with a PhD with significant practice experience in building and applying physiologically based pharmacokinetic (PBPK) models across a range of applications, ideally utilising GastroPlus.

Significant experience in biopharmaceutics, PK data analysis and modelling, metabolism and clinical pharmacology with an ability to relate a compound's in vitro physchem/biopharm/DMPK properties to preclinical and clinical in vivo performance.

Key Skills and Qualifications:

  • PhD in a relevant field
  • Significant experience in PBPK modelling
  • Strong understanding of biopharmaceutics, PK data analysis and modelling, metabolism and clinical pharmacology
  • Ability to relate in vitro properties to in vivo performance

How to Apply:

For more information, please contact Chris Gibson at Biopretium - chris.gibson@biopretium.com

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