Senior Gene Therapy Expert
3 weeks ago
Sr. Scientist Role Overview
About Spur Therapeutics:We are a clinical-stage biotech company focused on developing innovative, one-time treatments for serious and debilitating chronic diseases. Our integrated gene therapy platform includes in-house capabilities in research, protein engineering, and clinical development.
Job Responsibilities:This hybrid role involves working independently and as part of a team in a lab-based setting. Key responsibilities include setting up and handling bioreactors, manufacturing research/nonclinical grade viral vectors and recombinant proteins using mammalian cell suspension systems.
- Develop and optimize scalable upstream manufacturing processes using Design of Experiments (DoE)
- Lead the development of methods and protocols for viral vector manufacture
- Collaborate with internal CMC teams for transfer of manufacturing and quality aspects from Research to CMC
The ideal candidate will have a Ph.D. in a relevant discipline with >2 years of post-doctoral experience or at least 5 years of industry experience. They should have expertise in running bioreactors with suspension cultures of mammalian cells, particularly AAV manufacture.
Required Qualifications:Ph.D. in a relevant discipline with >2 years of post-doctoral experience or at least 5 years of industry experience. Scientific training and background in areas including bioreactor operation, viral vector manufacture, and biochemical analytical monitoring.
Estimated Salary:An estimated salary of £70,000 - £90,000 per annum, depending on experience, plus benefits including health insurance, retirement plan, and opportunities for professional growth.
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