Scientist 2 Position
4 weeks ago
Scientist 2
Location(s)
Cambridge (UK)
About Us
Revvity is a developer and provider of end-to-end solutions designed to help scientists, researchers, and clinicians solve the world's greatest health challenges. We pair the enthusiasm of an industry disruptor with the experience of a longtime leader. Our diverse team of 11,000+ colleagues from around the globe are vital to our success and the reason we're able to push boundaries in pursuit of better human health.
Job Summary
Revvity (formerly Horizon Discovery), is a leading life science company that delivers science-driven research solutions advancing the understanding of the genetic basis of disease and the delivery of better healthcare outcomes for patients. We act as a discovery partner for leading pharma and biotech companies worldwide, providing research services and tools to support the development of personalized medicines.
We are seeking a highly motivated and experienced Scientist 2 to join our Core Screening Department. As a Scientist 2 in the Preclinical department, you will be responsible for planning, executing, and analysing data generated from high-throughput compound screens and CRISPR-Cas9 functional genomic screens for fee-paying commercial clients. Your daily activities will directly align to and benefit Revvity's goals and values.
This role will be primarily lab based, with some office work required. Candidates will be expected to work on multiple tasks/projects simultaneously and should be highly self-motivated, able to work to tight timelines and be comfortable working under pressure in an environment with shifting priorities.
Key Responsibilities
• Contribute to the planning and delivery of arrayed compound screening projects, and pooled functional genomics screening projects, with appropriate supervision, where required.
• Design, QC and analyse high throughput arrayed compound screening projects.
• Manage compound arrayed screening activities in coordination with cell culture, compound management and automation scientists to ensure timely delivery of projects.
• Prepare client reports and support client project tracking and communication in collaboration with the project management office.
• Supervise more junior team members, mentoring them in techniques and troubleshooting problems.
• Contributing to continuous improvement of screening processes and workflows to maximise effectiveness and reduce costs.
Requirements
• Higher level degree (e.g. MSc, MRes or PhD) in Biotechnology or Biological discipline (or equivalent experience).
• Experience of mammalian cell culture, excellent aseptic technique and performing various cell-based assays, such as those commonly employed at Revvity (https://www.revvity.com/navigation/screening).
• Experience of handling large datasets and the interpretation and communication of these data to key internal and external stakeholders.
• Excellent interpersonal and communication skills, both written and verbal.
• Flexibility, adaptability, and ability to work in a dynamic matrix-managed team environment and on multiple projects with constantly changing priorities and deadlines.
• Excellent planning/organizational skills with a careful and meticulous nature.
• Ability to perform multiple tasks simultaneously, keep accurate records, follow and give instructions, and comply with company policies.
Desirable Skills
• Experience with transfection, transduction and techniques to modulate gene expression in mammalian cell models e.g. CRISPR-Cas9, siRNA, shRNA etc.
• Safe handling and production of lentiviral reagents.
• Familiarity with data visualisation software such as Prism and Tibco Spotfire.
• Knowledge of molecular biology techniques such as DNA extraction and PCR.
• Experience of high throughput screening and knowledge of combination screening, including analysing and interpreting compound dose response experiments.
• Knowledge of lab information management systems (LIMS) and liquid handling robotic equipment (although full training will be provided).
• Experience working in an Industrial / CRO setting.
What We Offer
Revvity offers a dynamic and supportive work environment, with opportunities for professional growth and development. We are committed to providing our employees with the tools and resources they need to succeed in their roles and advance their careers. If you are a motivated and experienced Scientist 2 looking for a new challenge, we encourage you to apply for this exciting opportunity.
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