Protein Biochemist Researcher

7 days ago


Slough, Slough, United Kingdom Next-Link Full time
Key Responsibilities

We are currently seeking an experienced protein biochemist with expertise in the expression and purification of a variety of recombinant proteins, including integral membrane proteins, for use in structural studies to join our Protein Expression & Purification Department at Next-Link. The successful candidate will have the opportunity to make a significant scientific contribution to exciting drug discovery projects.

Responsibilities:

  • Taking a lead role in the expression and purification of recombinant proteins, including multipass membrane proteins, for structural studies.
  • Communicating effectively within the protein group and across multiple disciplines, ensuring that information on work progress is relayed in a clear manner, highlighting any technical issues and providing potential solutions.
  • Staying up-to-date with and implementing technology developments within the area of protein expression and purification, especially techniques involved in the production of recombinant proteins, including multipass membrane proteins.
Requirements

We are looking for candidates who possess the following skill sets:

  • PhD holders or highly experienced Bachelor/MSc degree holders, with preference given to candidates who have spent time working within labs recognized for their expertise in the field of multipass membrane proteins.
  • Familiarity with insect and mammalian cell expression systems.
  • Independence in purification techniques, including affinity chromatography, ion exchange, SEC, and HIC.
  • Extensive working knowledge of AKTA purification platforms and associated software.
  • Comprehensive knowledge and experience with software used in manipulating protein and DNA sequences, as well as molecular visualization of proteins.
  • An excellent knowledge of the literature around the generation of recombinant proteins, including multipass membrane proteins, for structural studies.

Additionally, all applicants must possess excellent written and verbal communication skills.


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