Senior Process Development Scientist

6 days ago


London, Greater London, United Kingdom King's College London Full time

Job Title: Senior Process Development Scientist

Job Summary:

The King's College London Gene Therapy Vector Facility (GTVF) is seeking a highly skilled Senior Process Development Scientist to join our team. As a key member of our process development group, you will be responsible for the development and optimization of platform processes for viral vectors.

Key Responsibilities:

  • Develop and optimize platform processes for viral vectors
  • Work closely with colleagues in MSAT, Production, Quality Assurance, and Quality Control to ensure manufacturing processes are evaluated and optimized
  • Lead projects/programmes of work under the direction of the Head of Process Development/Technical Director
  • Propose targeted lab work to optimize processes prior to manufacture
  • Support risk assessments, biological safety evaluation, and identify and implement improvements in manufacturing processes

Requirements:

  • Experience of working in commercial companies within process development at Pharma/Biotech/Contract Manufacturing organisation (CMO) sectors
  • Experience gained in process development of viral vector purification demonstrating optimisation of processes by delivering improvements in yield, quality, and reproducibility
  • Experience of running analytical techniques to analyse and quantify viral vector titres and quality and working with cell culture techniques
  • Experience in using chromatography equipment and software
  • Design and execution of experiments using DOE software under the direction of a head of department or technical director and their implementation in Process Development

What We Offer:

  • A full-time post with an indefinite contract
  • A competitive salary and benefits package
  • The opportunity to work with a leading academic institution and contribute to the development of innovative gene therapies


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