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Babraham, Cambridgeshire, United Kingdom Cancer Research UK Full timeAbout Cancer Research UKWe are a world-leading charity dedicated to beating cancer through research and innovation. Our mission is to create a future where all cancers are cured, and we're looking for talented individuals to join our team.Job SummaryWe are seeking an experienced Group Leader to lead our Medicinal Chemistry team and drive our therapeutic...
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Babraham, Cambridgeshire, United Kingdom Cancer Research UK Full timeAbout Cancer Research UKWe are a world-leading charity dedicated to beating cancer through research and innovation. Our mission is to create a future where all cancers are cured, and we're looking for talented individuals to join our team.Job SummaryWe are seeking an experienced Group Leader to lead our Medicinal Chemistry team and drive our Therapeutic...
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Babraham, Cambridgeshire, United Kingdom Cancer Research UK Full timeAbout Cancer Research UKWe are a world-leading charity dedicated to beating cancer through research and innovation. Our mission is to create a future where all cancers are cured, and we're looking for talented individuals to join our team.Job SummaryWe are seeking an experienced Group Leader to lead our Medicinal Chemistry team and drive our Therapeutic...
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Babraham, Cambridgeshire, United Kingdom Cancer Research UK Full timeAbout the RoleWe are seeking an accomplished scientific and people leader to lead the Cell Pharmacology team within Mechanistic Pharmacology at our Babraham Research Campus facilities in Cambridge.The successful candidate will have a proven track record of recruiting, inspiring and developing a high-functioning team, and optimising team performance in a...
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Scientific Team Lead
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Babraham, Cambridgeshire, United Kingdom Cancer Research UK Full timeAbout the RoleWe are seeking an accomplished scientific and people leader to lead the Cell Pharmacology team within Mechanistic Pharmacology at Cancer Research UK.As the Group Leader, you will set and lead the Cell Pharmacology vision to help identify the right drugs with the right mechanisms for the right patients, faster.You will lead and drive a...
DMPK Group Leader
1 month ago
Cancer Research UK is seeking an experienced DMPK Group Leader to join our Drug Discovery team. As a key member of our team, you will be responsible for leading and driving our DMPK and translational modelling strategy.
Key Responsibilities- Design, propose and execute innovative experiments to positively impact projects and the overall direction of in vitro/in vivo science.
- Maintain awareness of external developments in the DMPK and PKPD fields and proactively suggest and evaluate new techniques.
- Design and implement new ways of working that have a direct impact on data quality and productivity.
- Contribute to the strategic leadership within the Medicinal Chemistry and DMPK group, as well as the overall Therapeutic Innovation research strategy.
- Effectively manage appropriate outsourcing activities.
- Effectively prioritise and co-ordinate multiple areas of work.
- Lead and drive a high-performing team to provide all aspects of DMPK and PKPD expertise.
- Manage internal expertise, capacity, and resources to drive governance and decision-making regarding scientific portfolio support and technology development.
- Communicate and share knowledge and expertise effectively within and across the organisation.
- Present and clarify results across departments and to alliance partners.
- Ensure a high level of data integrity within DMPK group.
- Lead drug discovery projects where appropriate.
- Be a recognised and passionate leader, able to represent the department across a broad range of therapeutic projects and cross-site initiatives, both internally as well as externally.
- Drive scientific and technical innovation, including through external collaboration and partnership.
- Ensure equality and diversity is celebrated and considered as part of all decisions taken.
We are looking for a highly experienced and skilled DMPK Group Leader with a strong background in pharmacokinetics, pharmacodynamics, and drug metabolism. You will have a PhD or equivalent experience in a relevant field and significant experience in DMPK aspects of drug discovery.
You will have a proven track record of delivering PK, PKPD and TKPD aspects to projects, including significant experience in translating drug-target kinetics through to mechanistic PKPD modelling for therapeutic dose prediction.
You will be an expert in specialist tools such as MATLAB, SimCYP, WinNonLin/Phoenix NLME and have a strong external reputation in translational PKPD modelling and DMPK.
You will have excellent interpersonal and communication skills coupled with strong leadership skills, ability to influence multiple stakeholders and collaborate across projects and sites.
What We OfferCancer Research UK offers a generous benefits package, a wide range of career and personal development opportunities and high-quality tools, policies, and processes to enable you to do your job well.
We are committed to equality, diversity and inclusion and welcome applications from people of all backgrounds and cultures.
We are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.
