Senior Analytical Scientist
3 weeks ago
**Job Overview:
We are seeking a highly experienced Senior Analytical Scientist to join our team in London, UK. As a key member of our Bioanalytical group, you will be responsible for developing and implementing robust analytical methods for the characterization of antibodies and ADCs.
**Responsibilities:
- Develop and implement analytical methods for protein and conjugate characterization, including stress testing, sequence liability analysis, and PTM/glycan profiling.
- Collaborate with cross-functional teams to optimize analytical protocols, including drug-to-antibody ratio (DAR) determinations.
- Partner with Antibody Engineering to innovate and characterize novel antibody and ADC formats.
- Communicate complex technical information effectively to both internal and external stakeholders.
- Contribute to the development of new technologies and methodologies to advance the field of bioanalysis.
**Requirements:
To be successful in this role, you will need:
- A BSc/MSc in Life Sciences or Chemistry with a strong foundation in Biochemistry.
- Mastery of mass spectrometry techniques (e.g., peptide mapping, DAR determination), proficiency with tools like MassHunter and Agilent systems.
- Expertise in LC-MS, HIC-HPLC, SEC, IEX, and RP-HPLC; experience with Chromeleon and Vanquish UHPLC systems is a bonus.
- Demonstrated ability to develop and troubleshoot analytical methods for protein and conjugate characterization.
- Strong understanding of biotechnology and pharmaceutical industries.
- Excellent interpersonal and communication skills.
**Compensation Package:
We offer a competitive salary of £70,000 per annum, plus benefits including annual travel allowance, performance-based bonus, 30 days of holiday, matched pension contributions, private health insurance, share options, and social incentives.
Salary: £70,000 per annum
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