Senior Research Scientist

1 week ago

Macclesfield, Cheshire East, United Kingdom Proclinical Staffing Full time

Job Title: Senior Scientist

Job Summary: We are seeking a highly skilled Senior Scientist to join our team at Proclinical Staffing. The successful candidate will be responsible for developing clinical assays for biomarkers at a market-leading medical devices organisation.

Key Responsibilities:

  • Develop targeted LC-MS methods on a triple quadrupole mass spectrometer to quantify phosphopeptide biomarkers.
  • Devise strategies for normalization and quality control to ensure test accuracy and reliability.
  • Collaborate with the product development team and quality manager to establish appropriate systems, monitoring, and documentation.
  • Author and contribute to regulatory submissions, technical protocols, and reports.
  • Maintain and calibrate LC-MS/MS systems, prepare buffers, and ensure quality control samples are run.
  • Document maintenance, calibrations, and QC work for reporting purposes.
  • Implement process improvements and contribute to team success.
  • Support lab-based team duties during colleagues' absences and additional pressure periods.

Requirements:

  • PhD (or equivalent experience) in a relevant or STEM-based subject.
  • Hands-on experience with high-end LC-MS/MS systems, including calibration, maintenance, and quality control.
  • Specific experience with triple quadrupole mass spectrometers and developing targeted methods.
  • Expertise in developing clinical assays using LC-MS/MS proteomic technologies.
  • Proficiency in interrogating LC-MS/MS raw data using vendor software (e.g., Thermo's Xcalibur/Freestyle/Chromeleon, or SciexOS).
  • Strong communication, teamwork, organizational, and time management skills.
  • High degree of personal motivation and willingness to learn new skills and undertake relevant training.

How to Apply: If you are interested in this exciting opportunity, please complete the form below and attach a copy of your CV. Alternatively, for further details or to talk directly to a life sciences recruitment specialist, please request a call back at the top of this page.

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