Current jobs related to Senior Scientist, Viral Vector Manufacturing - London, Greater London - Orchard Therapeutics


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the RoleOrchard Therapeutics is a global gene therapy leader focused on transforming the life of patients with rare disorders through innovative gene therapies based on gene-modified hematopoietic stem cells (HSC). We are seeking an experienced Scientist II, Viral Vector Development to join our team in London.The successful candidate will support the...


  • London, Greater London, United Kingdom Royal Free London NHS Foundation Trust Full time

    Job Description:The Royal Free London NHS Foundation Trust is seeking a highly skilled Viral Vector Manufacturing Specialist to support the development and implementation of novel intermediate scale lentiviral manufacturing techniques in suspension cell bioreactors. As a key member of our team, you will play a crucial role in building and qualifying a GMP...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    Orchard Therapeutics is a global gene therapy leader focused on transforming the lives of patients with rare disorders. We are seeking a skilled Principal Scientist to join our Technical Development team in Hammersmith, London.The ideal candidate will have a strong background in cell and gene therapy, with expertise in designing and developing processes for...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    We are a global gene therapy leader focused on transforming the lives of patients with rare disorders through innovative therapies based on gene-modified hematopoietic stem cells. Our Technical Development team sits within Technical Operations and is responsible for the development and characterization of Lentiviral Vectors (LVVs) and DS/DP production...

  • Principal Scientist

    4 weeks ago


    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Join Orchard Therapeutics as a Senior Scientist in our Cell and Gene Therapy team in Hammersmith, London.We are looking for an experienced professional with a strong background in biotechnology, process development, or a related field. The ideal candidate will have a minimum of 5 years of experience in viral vector development, manufacture, and delivery,...


  • London, Greater London, United Kingdom Royal Free London NHS Foundation Trust Full time

    Role OverviewWe have an exciting opportunity for a skilled Lentiviral Manufacturing Engineer to join our team at the Royal Free London NHS Foundation Trust. This role involves supporting the development and implementation of novel lentiviral manufacturing techniques in suspension cell bioreactors.The successful candidate will work closely with our...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the JobAs a Scientist II, Viral Vector Development at Orchard Therapeutics, you will support the Principal Scientist in the development of innovative, high-yield processes for production of lentiviral vectors. You will also compile process data, prepare databases to analyze results, confirm scientific hypotheses, and propose new experiments.Key...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the RoleThis is an exciting opportunity to join our global gene therapy leader as a Viral Vector Development Lead. You will lead the development of upstream and downstream processes for LVVs to deliver robust manufacturing platforms for early and late-stage clinical and commercial development.You will be responsible for compiling process data,...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    About the CompanyOrchard Therapeutics is a global gene therapy company with a diverse and dynamic work environment. Our Technical Development team sits within Technical Operations and is responsible for the development and characterization of Lentiviral Vectors (LVVs) and DS/DP production processes.We require an experienced Scientist II, Viral Vector...


  • London, Greater London, United Kingdom King's College London Full time

    About King's College LondonThe Gene Therapy Vector Facility at King's is a leading institution in the field of gene therapy, manufacturing viral vectors for various cancers and rare diseases. As a full-time Manufacturing Senior Scientist, you will be part of an indefinite contract with 35 hours of work per week.Required Skills and QualificationsA strong...

  • GMP Scientist

    2 weeks ago


    London, Greater London, United Kingdom NHS Full time

    About the PositionWe are looking for a talented GMP Scientist to play a key role in building and qualifying a GMP process from the ground up. This position requires strong experience in viral vector manufacture and scale-up, as well as analytical assays.The ideal candidate will have a strong background in research and development, with experience in cell...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    Job DescriptionWe are seeking a highly skilled Senior Process Development Scientist to join our Technical Development team at Orchard Therapeutics. The successful candidate will be responsible for the development and characterization of Lentiviral Vectors (LVVs) and DS/DP production processes.This is an exciting opportunity for a motivated individual to work...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    We are looking for a highly motivated and organized individual to join our Technical Operations team as a Scientist II, Viral Vector Development.In this role, you will support the design, development and improvement of upstream and downstream processes for Lentiviral Vectors (LVVs) to deliver robust manufacturing platforms for early and late-stage clinical...


  • London, Greater London, United Kingdom King's College London Full time

    About UsKings' College London is a world-renowned research-intensive university with a rich history and heritage. The Gene Therapy Vector Facility at King's is a state-of-the-art facility dedicated to the manufacture of viral vectors for novel therapies. Our mission is to push the boundaries of science and medicine to deliver innovative solutions for...

  • Senior Scientist

    4 weeks ago


    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Are you a highly motivated and experienced professional looking for a new challenge?We are seeking a skilled Viral Vector Process Developer to join our Technical Development team at Orchard Therapeutics in Hammersmith, London.The ideal candidate will have a strong background in biotechnology, process development, or a related field, with a minimum of 5 years...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    As a Regulatory Scientist in Cell and Gene Therapy, you will play a critical role in ensuring that our products meet the highest standards of quality and regulatory compliance.You will be responsible for providing expert review and approval of executed batch records, test records, and associated documentation for release of LVVs and plasmids used in their...


  • London, Greater London, United Kingdom Royal Free London NHS Foundation Trust Full time

    Job SummaryWe are seeking a highly skilled Viral Vector Specialist to join our team at the Royal Free London NHS Foundation Trust. This is an exciting opportunity for a talented individual to support the development and implementation of novel lentiviral manufacturing techniques in suspension cell bioreactors.The successful candidate will be responsible for...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    Lentiviral Vector Production Technician Job DescriptionAs a key member of the Translational Research Team at Orchard Therapeutics, the successful candidate will play a crucial role in supporting the production of Lentiviral Vectors. This involves working closely with the team to plan and conduct routine lentiviral production runs, ensuring laboratory...

  • Molecular Biologist

    2 weeks ago


    London, Greater London, United Kingdom Orchard Therapeutics Full time

    Orchard Therapeutics is a leader in the field of cell and gene therapy, and we are now seeking an experienced Research Technician to join our Translational Research Department. The successful candidate will have a strong background in cellular and molecular biology, with experience working with lentiviral vectors.This role involves a range of exciting...


  • London, Greater London, United Kingdom Orchard Therapeutics Full time

    Orchard Therapeutics is a global leader in gene therapy, focusing on developing innovative treatments for rare disorders. We are seeking a highly skilled Senior Gene Therapy Process Developer to join our team in London.This role will involve the development of high-yield processes for the production of Lentiviral Vectors (LVVs). You will work closely with...

Senior Scientist, Viral Vector Manufacturing

3 weeks ago


London, Greater London, United Kingdom Orchard Therapeutics Full time
About Our Team
We are a dynamic and multidisciplinary team within Technical Operations at Orchard Therapeutics responsible for the development and characterization of Lentiviral Vectors (LVVs) and DS/DP production processes. Our team is dedicated to delivering robust manufacturing platforms for early and late-stage clinical and commercial development.

We are looking for a Senior Scientist, Viral Vector Manufacturing to support the Principal Scientist in the development of innovative, high-yield processes for production of lentiviral vectors. The ideal candidate has experience in biotechnology or pharmaceutical industry with a primary focus on the process development and manufacturing of viral vectors, preferably retro and lentiviral vectors.

Key Responsibilities
* Support the Principal Scientist in the development of innovative, high-yield processes for production of lentiviral vectors
* Compile process data, prepare databases to analyze results, confirm scientific hypotheses, and propose new experiments
* Prepare, review, and complete study reports and protocols/SOPs
* Assist with CMC and regulatory submissions

Requirements
* Experience in biotechnology or pharmaceutical industry with a primary focus on the process development and manufacturing of viral vectors
* Knowledge in bioprocessing, purification of viral vectors, and virology
* Proficiency with MS office, MFCS, SnapGene, Unicorn, electronic lab-books, and/or other commonly used software

What We Offer