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Postdoctoral Researcher in Pharmacometrics
2 months ago
CK Group is seeking a highly skilled Postdoctoral Researcher to join their team in Bracknell, UK. The successful candidate will play a key role in high-impact research endeavors spanning from discovery to advanced clinical development of Antibody Drug Conjugates (ADC).
Key Responsibilities:- Establish the appropriate dose and regimen to achieve better therapeutic index and understand the preliminary dosing requirements.
- Develop a comprehensive and flexible framework (Clinical Utility Index) for modeling ADC PK/PD and the Exposure-Response relationship in both preclinical and clinical settings.
- Collaborate with the research team to design and execute experiments to support the development of ADCs.
- PhD in Pharmacometrics, Pharmaceutical/Biomedical Sciences, Computational Sciences, Engineering, or a related discipline.
- Experience using relevant software such as R, Monolix, NONMEM, MATLAB, or similar.
- Experience in QSP, PK/PD, exposure-response modeling or other modeling & simulation related discipline.
- Understanding of pharmacokinetics and/or pharmacodynamic principles.
- Proficient in data analysis and reporting.
Our client is one of the largest pharmaceutical companies in the world, focused on finding answers for some of the world's most urgent medical needs.
Location:This role is based at our client's site in Bracknell, UK. The successful candidate will be required to work on-site two times per week.