Scientific Researcher
3 weeks ago
We are seeking a highly skilled and motivated bench scientist to join our respiratory biology team within the Respiratory and Immunology Research Unit (RIRU) at GSK. The successful candidate will be responsible for designing and delivering advanced biology assays to address key biological questions needed to progress respiratory drug discovery programs across disease indications, including COPD and ILD.
Key Responsibilities:- Develop and implement respiratory-relevant cell-based assays to evaluate the function of potential drug targets in disease-relevant cells via pharmacological modulation and/or genetic manipulation.
- Write protocols, design and execute biology-focused experimental studies, applying advanced data analysis, interpreting data, compiling reports and communicating findings to project teams to progress projects and/or develop platforms.
- Build the biological rationale and generate scientific hypotheses to inform experimental design and approaches to support both new target work packages and later stage assets within the respiratory portfolio.
- Work collaboratively in a matrix team and within a cross-functional environment to develop and carry out selected experiments to address key biological questions aligned to project goals within agreed timelines.
- Maintain a high level of documentation for all experimental work aligned with data integrity expectations.
- PhD or equivalent experience in Respiratory Biology, Cell Biology, Molecular Biology, and/or Immunology.
- Proficiency in designing, executing and interpreting experimental studies across a wide range of laboratory techniques gained from working in industrial or academic research environments.
- Experience of standard laboratory techniques, including cell culture, optimisation and execution of cell-based assays, molecular biology, RNA isolation, RT-qPCR analysis, protein analysis, imaging and flow cytometric techniques.
- Strong written and verbal communication skills, with the ability to effectively present scientific findings to multidisciplinary internal and external stakeholders in a balanced, clear, and precise manner.
- Proven ability to balance priorities across multiple objectives, meeting timelines while maintaining attention to detail and high-performance standards.
- Experience with data analysis software and knowledge of statistical analysis methodology and bioinformatics tools.
- Prior experience with establishing disease-relevant in vitro models of respiratory disease or in respiratory biology such as human bronchial epithelial culture.
- Good understanding of drug discovery, ability to influence project direction by interpreting results outside area of expertise.
- Track record of scientific innovation as evidenced by effective support of drug discovery projects, peer-reviewed publications, conferences, reports or patents.
We believe in an agile working culture for all our roles. As an Equal Opportunity Employer, we are open to all talent and ensure that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.
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