Associate Principal Scientist, External Discovery Chemistry

1 month ago

London, Greater London, United Kingdom Merck Gruppe - MSD Sharp & Dohme Full time

Role Overview:

The Associate Principal Scientist will join several Discovery Chemistry programs as a team member/leader, responsible for the integration of external Contract Research Organization (CRO) group contributions to program objectives. You will have highly developed skills in medicinal and synthetic chemistry and in the efficient management of scientific resources. In this exciting role, you will be embedded with our company's internal programs teams, advancing program goals from identification of tool molecules to invention of novel clinical candidates. You will also play a critical role in building and developing our network of CRO partners in the UK and Europe.

Key Responsibilities:

  • Collaborate with Discovery Chemistry project teams across our company's network in building structure-activity relationships
  • Provide innovative design of therapeutic compounds
  • Planning and oversight of synthetic chemistry routes
  • Direct teams of contract research scientists toward meeting program objectives
  • Collaborate via electronic communication with CRO groups in multiple international time zones
  • Manage, nurture, and build our relationships with key CRO partners in the UK and Europe, focusing on growth, skill, and capability development, and technology sharing
  • This role requires strong oversight skills to ensure business continuity while fostering a collaborative partnership that drives mutual success
  • This position will require both domestic and international travel for multi-day site visits and working sessions with CRO groups in our global CRO partner network

Requirements:

  • Ph.D. preferred in Chemistry, Biochemistry, or related field
  • Candidates will have significant industry experience (e.g., pharma, biotech, CRO)
  • Industry experience in Organic Synthesis or Drug Discovery
  • Proven record of accomplishments in synthetic organic chemistry and/or medicinal chemistry
  • Expert proficiency in mining scientific literature and databases
  • Effective communication and collaboration skills in a team environment

Additional Information:

Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At our company, we're inventing for life.

Our Company:

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we 'follow the science' that great medicines can make a significant impact on our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to identify a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities, and robust scientific methodology, we collaborate to discover the next medical breakthrough.

Our Values:

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively for the common good. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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