Senior Research Scientist, Protein Degradation and Cancer

5 days ago

Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

We are seeking a highly skilled Senior Research Scientist to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology aspects of our projects, focusing on target validation and discovery of novel molecular glue and PROTAC targets for challenging oncology indications.

Key Requirements

  • A PhD in biology or biochemistry with a solid background in cancer cell biology and hands-on experience with in vitro genetic manipulation techniques applicable for target validation and interrogation of cell signalling pathways.
  • Experience in targeted protein degradation, biochemical and pharmacology assays would be an additional advantage.

Department Information

The Centre for Protein Degradation is a leading research group specialising in developing novel drug modalities that re-wire tumour cells' signalling by targeted degradation of key oncogenic drivers. Our experienced biologists work closely with medicinal chemists, biophysicists, computational scientists and oncology specialists on expanding the repertoire of novel degradable drug targets and E3 ligases, identifying drugs using innovative screening platforms and characterising their mechanisms of action.

We encourage all applicants to look at the attached job pack for more detailed information about this role. For an informal discussion about the role, please feel free to contact Dr Agnieszka Konopacka, Group Leader, Induced Proximity Therapeutics, via email: Agnieszka.Konopacka@icr.ac.uk.

  • Postdoctoral Research Fellow in Targeted Protein Degradation

    1 week ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly motivated Postdoctoral Training Fellow to join our team in the Centre for Protein Degradation at The Institute of Cancer Research. The successful candidate will work on the discovery and validation of novel molecular glue and PROTAC targets and E3 ligases for challenging oncology indications, contributing to our drug discovery...

  • Postdoctoral Research Fellow in Targeted Protein Degradation

    2 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title:Postdoctoral Training Fellow, Target and E3 Ligase Discovery, Biology, CPDJob Summary:We are seeking a highly motivated Postdoctoral Training Fellow to join our team in the Centre for Protein Degradation at The Institute of Cancer Research. The successful candidate will work on the discovery and validation of novel molecular glue and PROTAC targets...

  • Postdoctoral Research Fellow in Targeted Protein Degradation

    5 days ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly motivated Postdoctoral Training Fellow to join our team in the Centre for Protein Degradation at The Institute of Cancer Research. The successful candidate will work on the discovery and validation of novel molecular glue and PROTAC targets and E3 ligases for challenging oncology indications.Key Responsibilities:Conduct research on...

  • Postdoctoral Research Fellow in Targeted Protein Degradation

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title:Postdoctoral Training Fellow, Target and E3 Ligase Discovery, Biology, CPDJob Summary:We are seeking a highly motivated Postdoctoral Training Fellow to join our team in the Centre for Protein Degradation. The successful candidate will work on the discovery and validation of novel molecular glue and PROTAC targets and E3 ligases for challenging...

  • Postdoctoral Research Fellow in Targeted Protein Degradation

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title:Postdoctoral Training Fellow, Target and E3 Ligase Discovery, Biology, CPDJob Summary:We are seeking a highly motivated Postdoctoral Training Fellow to join our team in the Centre for Protein Degradation. The successful candidate will work on the discovery and validation of novel molecular glue and PROTAC targets and E3 ligases for challenging...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    4 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    4 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    2 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    4 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job Title: Higher Scientific Officer, Target and E3 Ligase Discovery, BiologyWe are seeking a highly skilled and motivated Higher Scientific Officer to join our Centre for Protein Degradation, a part of the Institute of Cancer Research's Centre for Cancer Drug Discovery. The successful candidate will be working in a multidisciplinary team to deliver biology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    1 week ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled Senior Research Scientist to join our multidisciplinary team at the Centre for Protein Degradation. The successful candidate will be responsible for delivering biology aspects of our projects, focusing on target validation and discovery of novel molecular glue and PROTAC targets and E3 ligases for challenging oncology...

  • Senior Research Scientist, Target and E3 Ligase Discovery, Biology

    7 days ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled Senior Research Scientist to join our multidisciplinary team at the Centre for Protein Degradation. The successful candidate will be responsible for delivering biology aspects of our projects, focusing on discovery and validation of novel molecular glue and PROTAC targets and E3 ligases for challenging oncology indications.Key...

  • Senior Research Scientist

    6 days ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    Job SummaryWe are seeking a highly skilled and experienced Senior Research Scientist to join our team as the Head of Biology and Director of the Centre for Target Validation. The successful candidate will have a strong background in cancer biology and leadership experience in drug discovery within the pharmaceutical or biotechnology industry.Key...

  • Senior Research Scientist

    4 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled and dedicated Higher Scientific Officer to join our Integrative Cancer Epidemiology team at The Institute of Cancer Research. The successful candidate will lead the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations Study.Key ResponsibilitiesThe Higher...

  • Senior Research Scientist

    4 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled and dedicated Higher Scientific Officer to join our Integrative Cancer Epidemiology team at The Institute of Cancer Research. The successful candidate will lead the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations Study.Key ResponsibilitiesThe Higher...

  • Senior Research Associate

    1 month ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled and dedicated Higher Scientific Officer to join our Integrative Cancer Epidemiology team at The Institute of Cancer Research.About the RoleThe successful candidate will be responsible for leading the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations...

  • Senior Research Associate

    1 month ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled and dedicated Higher Scientific Officer to join our Integrative Cancer Epidemiology team at The Institute of Cancer Research.About the RoleThe successful candidate will be responsible for leading the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations...

  • Senior Biomedical Research Officer

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled Higher Scientific Officer to lead the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations Study.This role requires collaboration with pathologists, data scientists, and research administrators working closely with the Generations Study Team in Sutton...

  • Senior Biomedical Research Officer

    3 weeks ago

    Sutton Coldfield, Birmingham, United Kingdom The Institute of Cancer Research Full time

    We are seeking a highly skilled Higher Scientific Officer to lead the management of biological specimens and digital pathology processes for a large-scale prospective cohort study, The Generations Study.This role requires collaboration with pathologists, data scientists, and research administrators working closely with the Generations Study Team in Sutton...