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Senior Molecular Biologist

2 months ago


Guildford, Surrey, United Kingdom Angle Plc Full time
Job Title: Senior Molecular Biologist

ANGLE Plc is a world-leading liquid biopsy company commercialising a patent-protected platform technology that can capture rare circulating tumour cells (CTCs) from blood, in a minimally invasive way, for downstream analysis.

The company's Parsortix system is FDA cleared for its intended use in metastatic breast cancer and is currently the first and only FDA cleared medical device to harvest intact circulating cancer cells from blood. Parsortix technology comprises a microfluidic device that captures CTCs from blood based on their size and compressibility. Once harvested, the CTCs can be comprehensively analysed to provide a wealth of information about the patient's tumour, advancing cancer research and potentially personalised medicine.

Key Responsibilities:
  • Hands-on laboratory work, primarily in the area of Molecular Biology, including blood processing, Nucleic Acid extraction, PCR, NGS library prep and NGS processing.
  • Contribute to the writing of ESs and reports where relevant, and the writing and updating of SOPs when required.
  • Responsible for data collection, recording, processing, analysis and reporting.
  • Responsible for on-time and on-budget delivery of work packages within a project, including timely reporting of progress on projects and on metrics to monitor and mitigate risk and to ensure product deadlines are met.
  • Provide scientific and technical support to projects.
  • Responsible for quality and regulatory compliance of work undertaken.
  • Independently keep a current base knowledge in relevant areas of scientific and technical research.
  • Manage the day-to-day running of assigned projects within the Quality Management System (ISO13485) and work to the New Product Development (NPD) operating procedure.
  • Undertake additional ad-hoc tasks as required.
Requirements:
  • Bachelor in Life Sciences with relevant laboratory experience or Masters in Life Sciences, with laboratory experience in Oncology or Molecular Biology (preferably gained in the in vitro diagnostics assay development/validation industry).
  • Manage and deliver product development projects to agreed performance specifications, on time and within budget.
  • Good report writing skills, with the ability to communicate results to technical and non-technical staff.
  • Experience working to strict quality standards such as Medical Device Regulations including, but not limited to, 21 CFR 820, ISO 13485, 93/42/EEC, IVD 98/79 EC, ISO14971, GMP, GLP, QSR. A strong understanding of the importance of accurate record-keeping within a strictly controlled quality system is essential.
  • Ability to work both independently with minimal supervision as well as in a team environment.
  • An eye for detail and commitment to high-quality data.
  • A flexible, can-do approach to the requirements of the job.

Due to the nature of the role, our requirement is for this position to be Guildford-based, office hours, five days per week.

As a member of our highly skilled team you will receive opportunities for training and development and a competitive benefits package.

Please let us know if you require disability-related accommodation during the recruitment process so that we can work with you to meet your needs.