Senior Cell Processing and Gene Modification Scientist

3 weeks ago


Edinburgh, Edinburgh, United Kingdom RoslinCT Full time
Job Title: Associate Principal Development Scientist - Cell Processing and Gene Modification Lead

We are RoslinCT, a world-leading cell and gene therapy contract development and manufacturing organisation creating cutting-edge therapies that change people's lives.

As a key member of our Process Development team, you will provide leadership to the Cell Processing and Gene Modification team, driving the development of cell product manufacturing unit operations.

Key Responsibilities:
  • Provide strategic scientific leadership in a hands-on setting, sharing cell culture work and providing practical technical SME support to others in the Process Development Cell Processing and Gene Modification team.
  • Ensure strategic alignment with the Chief Scientific and Technology Officer, Innovation, and QC departments.
  • Develop cell product manufacturing unit operations, including apheresis processing, target cell selection, cell differentiation or activation, cell engineering, delivery methods (e.g., electroporation), cell expansion, harvest, formulation, and cryopreservation.
  • Collaborate with Business Development to scope/cost new projects and win new business.
  • Develop plans for method development, transfer, and qualification.
  • Stay abreast of global Cell and Gene Therapy/Sterile Manufacturing regulatory guidelines and trends.
  • Formulate realistic, tangible plans and solutions aligned with multi-project deliverables.
  • Directly manage Cell Processing and Gene Modification Scientists, including recruitment, training, and performance management.
  • Ensure quality, compliance, and good laboratory practices (non-GMP and GMP).
  • Manage change, including work patterns, project scopes, and ad hoc events.
  • Review technical reports, investigations, complex change controls, deviations, and risk assessments.
  • Promote high standards of good laboratory practices and technical report writing.
  • Own and influence policies and procedures relevant to your area of responsibilities.
  • Maintain professional communication with colleagues, client representatives, and the wider scientific community.
Requirements:
  • Hands-on experience in Cell and Gene Therapy cell process development and current technologies.
  • Familiarity with cell product manufacturing unit operations, including apheresis processing, target cell selection, cell differentiation or activation, cell engineering, delivery methods (e.g., electroporation), cell expansion, harvest, formulation, and cryopreservation.
  • Exceptional organisational, time management, and computer skills (Microsoft Word and Excel).
  • A Life Sciences Degree, Master, or PhD in a related subject, with previous experience in a CDMO manufacturing-focused environment.

We offer a competitive company pension scheme, 31 days of annual leave, plus 4 public holidays, and a range of flexible benefits to support your wellbeing and career development.



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