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Senior Scientist

4 weeks ago

Slough, Slough, United Kingdom Lonza Full time

At Lonza, we're committed to innovation and excellence in life sciences. We're seeking an experienced cell biologist to join our team of experts in Cell Culture Media Development as a Senior Scientist. This is a unique opportunity to contribute to the development of cell culture media for producing biologically active proteins, monoclonal antibodies, and biosimilars.

Key responsibilities:

  • Work closely with the Head, Media R&D Slough, to plan and prioritize tasks and assignments in a work program.
  • Understand and manipulate GS-CHO cell cycle regulation in vitro to develop cell culture media.
  • Execute experimental plans, analyze experimental data, and write technical reports.
  • Ensure that studies are scientifically sound and in line with current regulatory guidance and expectations.
  • Contribute scientific expertise and propose new ideas and product concepts targeting the research market.
  • Ensure GLP and EHS regulations are followed.

Key requirements:

  • Minimum of BSc in Biotechnology / Biochemistry or other related fields (MSc desirable).
  • Knowledge of CHO cell biology, cell cycle regulation, CHO cell metabolism is highly desirable.
  • Knowledge of basic cell biology techniques, i.e., mammalian cell culture, Flow Cytometry, Western blotting, RT-PCR, confocal microscopy, etc. is highly desirable.
  • Experience with high-throughput small scale bioreactors, i.e., ambr15, ambr250 is advantageous.
  • Good understanding of upstream processes, including fed-batch and perfusion cultures.
  • Knowledgeable of the current best practices for developing cell culture media, including metabolomics, metabolic flux analysis.
  • Technological background in mammalian cell line development and cell culture process development.
  • Strong interpersonal, presentation, time management, organizational, and written/oral communication skills are highly desirable.
  • Previous experience working in cross-matrixed/functional teams and ability to work on complex effectively and collaboratively in a matrixed environment is an asset.
  • Ability to successfully complete complex projects will be viewed favourably.
  • Inventiveness, enthusiasm, motivation, and problem-solving skills to develop new technical capabilities and solve challenging problems are assets.

At Lonza, we respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. We offer the satisfaction that comes with improving lives all around the world and making a meaningful difference.