Lead Protein Characterization Specialist

1 day ago


Denham, Buckinghamshire, United Kingdom Lonza Full time
Job Title: Lead Protein Characterization Specialist

About the Company:

Lonza is a global leader in life sciences operating across five continents. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people.

We are looking for a highly skilled Lead Protein Characterization Specialist to join our team at Lonza. As a specialist, you will lead major or complex work/projects simultaneously, develop innovative LC MS/MS solutions for protein characterization, and provide support and mentoring to junior colleagues.

Responsibilities:

  • Develop and execute analytical studies, interpret complex datasets, and identify and implement innovative LC MS/MS solutions for protein characterization.
  • Collaborate with peers across teams to ensure meticulous execution of projects and proactive identification of technical and operational improvements.
  • Communicate with external customers to demonstrate Lonza's scientific credibility and grow relationships.
  • Input into department technology strategy and support the Characterisation team in maintaining offerings in line with industry and regulatory expectations.
  • Execute assigned assays with a focus on safety, quality, timeliness, and accuracy adhering to regulatory requirements, where appropriate.
  • Complete and peer review laboratory documentation and perform technical reviews of assays to support reference standard and biochemical comparability studies.

Requirements:

  • Extensive and proven experience in developing and troubleshooting analytical methodology for protein analysis with a key focus on Mass Spectrometry.
  • Familiarity with a range of mass spectrometry platforms such as Quadrupole Orbitrap MS, Tribrid Orbitrap MS, or Q ToF MS.
  • Proven record of leading method development projects for protein analysis including experimental design, execution, and interpretation of complex datasets.
  • Experience with a range of analytical methods for protein characterisation such as liquid chromatography (e.g., RP, SEC, HILIC), capillary electrophoresis, and LC MS/MS.
  • Theoretical knowledge of protein chemistry and protein structure (primary and higher-order structure).
  • Capability to critically analyse data, interpret results, and communicate outcomes to external customers and internal stakeholders.

Salary Range: £55,000 - £75,000 per annum.



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