Postdoctoral Research Fellow

1 month ago

London, Greater London, United Kingdom The Francis Crick Institute Full time
Job Title: Postdoctoral Fellow

We are seeking a highly motivated and talented Postdoctoral Fellow to join our team at the Francis Crick Institute. The successful candidate will have a strong background in virology, cell biology, or molecular biology and will be responsible for investigating the function and cellular targets of the HIV Vpr protein during HIV-1 replication.

About the Role

The Postdoctoral Fellow will work closely with Dr. Kate Bishop and her team to investigate the molecular events that occur when a retrovirus infects its target cell. The project will focus on Vpr-induced DNA damage and its effects on chromatin, but all aspects of Vpr biology may be explored.

Key Responsibilities
  • Design and execute experiments to investigate the function and cellular targets of Vpr
  • Conduct molecular biology and biochemical techniques to study Vpr-induced DNA damage and its effects on chromatin
  • Collaborate with other researchers in the lab and with external collaborators to advance the project
  • Guide PhD students in their research and contribute to the development of their projects
  • Present research findings at scientific meetings and write papers for publication in referred journals
Requirements
  • PhD in virology, cell biology, or molecular biology
  • Good knowledge and understanding of retrovirology
  • Expertise in molecular biology and biochemical techniques
  • Expertise in cell culture and transfection
  • Pro-active in innovation and problem-solving
  • Experience of experimental design
  • Track record of writing papers as evidenced by publications or submitted manuscripts in referred journals
  • Ability to work independently and also capable of interacting within a group
Desirable Qualifications
  • Experience working with primary cells
  • Experience in microscopy
  • Experience in flow cytometry
  • Good understanding of bioinformatics
  • Research experience of DNA damage pathways
  • Research experience of viral accessory proteins or innate immunity
What We Offer

The Francis Crick Institute is a world-leading research organization that is committed to advancing our understanding of biology and to using that knowledge to combat major diseases. We offer a dynamic and supportive work environment, with access to state-of-the-art facilities and a wide range of training and development opportunities.

We are an equal opportunities employer and welcome applications from all backgrounds. We are committed to providing equal employment opportunities, regardless of ethnicity, nationality, gender, sexual orientation, gender identity, religion, pregnancy, age, disability, or civil partnership, marital or family status.

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