Senior Bioinformatics Specialist

2 weeks ago

Hinxton, United Kingdom Wellcome Sanger Institute Full time
About the Role

We are seeking a Senior Bioinformatician to support single-cell and spatial transcriptomic studies needed to train large-scale AI-based foundation models as part of a collaborative project with Open targets. This role will aid multiple computational projects across the lab, focusing on curating large-scale cohorts of training data to train foundation models.

The post holder will maintain a key understanding of the research portfolio within the team and contribute to the development of innovative and creative data analysis strategies. They will also contribute to the development of the training pipeline and machine learning and artificial intelligence models.

The successful candidate will have the opportunity to develop their skills in machine learning and AI models and explore opportunities to transition project-based analysis work into established scalable pipelines. They will also be responsible for advocating for open and reproducible science.

This is an exciting opportunity to work in single-cell and spatial genomics to understand how the immune system develops and maintains health.

Key Responsibilities
  • Help generate and lead data analysis, and interpret large single-cell genomics data relating to the Human Cell Atlas research generated by the group, shared by collaborators and publicly available, including multi-omic and spatial datasets.
  • Implement innovative and creative data analysis strategies to aid in the pursuit of biological insights and clinical translation using single-cell research.
  • Work in a team to answer research questions formulated together with the members of Haniffa Lab, and with team members across the wider Institute as appropriate.
  • Organise and keep track of developed codes and generated data within the group.
  • Feedback results to project leaders when required to achieve deadlines.
  • Prepare high-quality data reports and manuscripts to communicate results, including through publication and presentations at scientific meetings.
About You

You are a bioinformatician with experience analysing genomic data and interpreting biological data. You are seeking a senior role that includes elements of statistical analysis, data analysis and pipeline engineering. You are a highly detail-oriented problem solver and are eager to learn and develop in the areas in which you have less experience.

You will be supported in your personal and professional development and have the opportunity to lead peer-reviewed publications on genetics and genomics approaches.

Essential Skills
  • MSC or PhD in a relevant quantitative discipline (e.g. Computational Biology, Genetics, Bioinformatics, Physics, Engineering or Applied Statistics/Mathematics); or equivalent working experience in Bioinformatics or a related discipline
  • Experience programming in high-level scripting languages (Preferably Python and/or R), and the Unix Shell
  • Understanding and some experience in the fields of genomics, data processing and high-throughput data analysis
  • Experience in single-cell genomics data analysis and integration, e.g. scRNAseq, scATAC (desirable)
  • Experience developing statistical/machine-learning methods for the analysis of large-scale biological datasets, particularly Gaussian processes, neural networks and deep generative models (desirable)
  • Extensive experience in a research environment with an established track record of productivity through publications, or writing reports in the industry
  • Enthusiastic, proactive attitude and desire to learn
  • Strong communication skills to allow efficient interactions with team members
  • Commitment, problem-solving skills and attention to detail
  • Ability to organise own workload and manage competing priorities
  • Ability to summarise complex information and present to a wide variety of audiences in a concise and logical manner
  • Demonstrates inclusivity and respect for all

  • Senior Bioinformatics Specialist

    4 weeks ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a highly skilled Senior Bioinformatician to join our team at the Wellcome Sanger Institute. As a key member of our Tree of Life Programme, you will play a pivotal role in developing innovative methods to assess rates of gene exchange across different lineages.Key ResponsibilitiesDesign and interpret complex statistical analyses...

  • Senior Bioinformatics Specialist

    4 weeks ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a highly skilled Senior Bioinformatician to join our team at the Wellcome Sanger Institute. As a key member of our Tree of Life Programme, you will play a pivotal role in developing innovative methods to assess rates of gene exchange across different lineages.Key ResponsibilitiesDesign and interpret complex statistical analyses...

  • Senior Bioinformatics Specialist

    2 weeks ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a Senior Bioinformatician to support single-cell and spatial transcriptomic studies needed to train large-scale AI-based foundation models as part of a collaborative project with Open targets. This role will aid multiple computational projects across the lab, focusing on curating large-scale cohorts of training data to train...

  • Senior Bioinformatics Specialist

    4 weeks ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a highly skilled Senior Bioinformatician to join our interdisciplinary team at the Wellcome Sanger Institute. As a key member of our team, you will play a crucial role in supporting single-cell and spatial transcriptomic studies, working closely with life scientists, computer scientists, and ML scientists to train large-scale...

  • Senior Bioinformatics Specialist

    4 weeks ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a highly skilled Senior Bioinformatician to join our interdisciplinary team at the Wellcome Sanger Institute. As a key member of our team, you will play a crucial role in supporting single-cell and spatial transcriptomic studies, working closely with life scientists, computer scientists, and ML scientists to train large-scale...

  • Senior Data Analyst

    8 hours ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    About the RoleWe are seeking a Senior Bioinformatician to support single-cell and spatial transcriptomic studies needed to train large-scale AI-based foundation models as part of a collaborative project with Open Targets.This role will aid multiple computational projects across the lab, focusing on curating large-scale cohorts of training data to train...

  • Postdoctoral Researcher

    3 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your primary objective will be to extract...

  • Postdoctoral Researcher

    3 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your primary objective will be to extract...

  • Senior Bioinformatician

    5 months ago

    Hinxton, United Kingdom Wellcome Sanger Institute Full time

    Do you want to help us improve human health and understand life on Earth? Make your mark by shaping the future to enable or deliver life-changing science to solve some of humanity’s greatest challenges.About the RoleWe are seeking a Senior Bioinformatician to support single-cell and spatial transcriptomic studies needed to train large-scale AI-based...

  • Postdoctoral Researcher

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your goal will be to extract disease mechanisms...

  • Postdoctoral Researcher

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your goal will be to extract disease mechanisms...

  • Postdoctoral Research Fellow

    3 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Postdoctoral Research FellowJoin the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL) as a Postdoctoral Research Fellow and contribute to the development of computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication.About the Role:Develop and apply...

  • Postdoctoral Researcher

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your goal will be to extract disease mechanisms...

  • Postdoctoral Researcher

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job Title: Post-docAs a postdoctoral fellow in the Saez Rodriguez group at the European Molecular Biology Laboratory (EMBL), you will play a key role in developing and applying computational methods and tools to study cellular organisation, gene regulation, and intra- and intercellular cell-cell communication. Your goal will be to extract disease mechanisms...

  • Pdbe Coordinator

    5 months ago

    Hinxton, United Kingdom European Molecular Biology Laboratory Full time

    Bioinformatics Hinxton, UK In this job Your role You have You might also have Why join us What else you need to know More about EMBL-EBI We are looking for an outstanding individual to coordinate the Protein Data Bank in Europe Team (PDBe; pdbe.org) team at the European Bioinformatics Institute (EMBL-EBI). This role is central for delivering data services...

  • Biocurator Specialist

    3 weeks ago

    Hinxton, United Kingdom EMBL-EBI Full time

    About the RoleWe are seeking a highly skilled Biocurator to join our Human Genomics Team at the EMBL European Bioinformatics Institute (EMBL-EBI). The team provides genome variation and regulation resources as part of the Ensembl project, human variation interpretation services including the DECIPHER platform, and data portals for partners around the...

  • Contract Management Specialist

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job SummaryWe are seeking a highly skilled and motivated individual to join our team as a Contract Management Specialist. The successful candidate will be responsible for developing and coordinating training courses, webinars, and knowledge-exchange workshops to support users of life science services in the context of grant-funded projects.Key...

  • Contract Management Specialist

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job SummaryWe are seeking a highly skilled and motivated individual to join our team as a Contract Management Specialist. The successful candidate will be responsible for developing and coordinating training courses, webinars, and knowledge-exchange workshops to support users of life science services in the context of grant-funded projects.Key...

  • Contract Management Specialist

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job SummaryWe are seeking a highly motivated and experienced Contract Management Specialist to join our team at the European Molecular Biology Laboratory (EMBL). As a key member of our training team, you will be responsible for developing and coordinating training courses, webinars, and knowledge-exchange workshops to support users of life science...

  • Contract Management Specialist

    4 weeks ago

    Hinxton, United Kingdom European Molecular Biology Laboratory (EMBL) Full time

    Job SummaryWe are seeking a highly motivated and experienced Contract Management Specialist to join our team at the European Molecular Biology Laboratory (EMBL). The successful candidate will be responsible for developing and coordinating training courses, webinars, and knowledge-exchange workshops to support users of life science services in the context of...