Senior Bioinformatics Engineer

3 days ago

Oxford, Oxfordshire, United Kingdom Immunocore Full time
Job Description

Job Title: Senior Bioinformatics Engineer

Job Summary:

We are seeking a highly skilled Senior Bioinformatics Engineer to join our team at Immunocore. As a Senior Bioinformatics Engineer, you will play a key role in developing and implementing algorithms, software tools, and databases for the analysis and interpretation of biological data.

Key Responsibilities:

  • Develop and maintain bioinformatic pipelines for processing and analyzing genomics, transcriptomics, and proteomics data.
  • Design and implement algorithms for biological data analysis.
  • Liaise with bioinformaticians and wider scientific teams to understand project requirements and translate them into technical solutions.
  • Optimize existing algorithms and software tools for performance, scalability, and accuracy.
  • Contribute to the development and maintenance of custom software applications, databases, and production-quality modules for the Immunocore pipeline database system.
  • Stay current with advances in bioinformatics and data science and integrate new methodologies into our workflows.
  • Collaborate with cross-functional teams to integrate bioinformatic solutions into broader research projects and workflows.
  • Provide training and supporting guides as required.
  • Implement the integration of commercial software tools and platforms where appropriate.

Requirements:

  • Deep understanding of Python.
  • Strong experience with SQL and database management systems (e.g. MySQL, PostgreSQL, Oracle).
  • Practical experience developing data processing pipelines.
  • Experience working in a Linux/Unix environment.
  • Familiarity with cloud infrastructure.
  • Experience with API design and usage.
  • Excellent communication and collaboration abilities.
  • Strong problem-solving skills and attention to detail.

Desirable:

  • Proven experience as a Data Engineer or in a similar role.
  • Skills in R programming.
  • Experience of pipeline development with knowledge of domain-specific languages, such as Nextflow and Snakemake.
  • Familiarity with bioinformatics tools and methodologies.
  • Exposure to the analysis of large biological omics-based datasets.
  • Professional experience in the development of web-based applications.
  • Experience with autoscaling cloud tools, or HPC.
  • Previously worked as part of a bioinformatics and/or software development teams.
  • Excellent version control habits.
  • Adept at writing comprehensive unit tests.
  • Experience in Agile methodology.
  • An interest in cancer, immunology, molecular biology, or genetics.
  • An ability to explain software development concepts to non-specialists.
  • Exposure to machine learning, with experience in building machine learning systems.

About Us:

Immunocore is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases, and autoimmune disease.

We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases, and autoimmune diseases.

We recognize that our employees are our greatest asset. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen.

We are dedicated to developing breakthrough therapies that transform patients' lives, advancing medicine, and supporting one another in these pursuits.

We are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.

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