Analytical Development Specialist

5 days ago


London, Greater London, United Kingdom Orchard Therapeutics Full time
Company Overview

Orchard Therapeutics is an international company focused on transforming the lives of patients with rare disorders through innovative gene therapies.


Job Description

The Global Analytical Development Team seeks a skilled Scientist to support analytical testing related to process development activities. Key responsibilities include:

  • Development and qualification of analytical methods applicable for cell and gene therapy programs.
  • Maintenance and completion of accurate lab-based records and final reports to support internal analytical assay development activities as required.
  • Performing and developing analytical methods including protein and cell-based tools, immunoassays and ddPCR.
  • Assessment of novel equipment and methodologies.
  • Tissue culture of primary cells, cell lines, as well as cell bank generation and appropriate record maintenance.
  • SOP-writing to support activities as required including tech transfer to internal departments or external partners.
  • Presentation of method development plans and results to the wider department and functional teams as requested.
  • Support development and qualification of analytical methods at CMOs and CTOs as required.

Salary

Estimated annual salary: £50,000-£60,000.


Required Skills and Qualifications

The successful candidate will either possess a PhD with >1 year post-doc experience or equivalent level of experience in industry following BSc/MSc in biotech-related discipline. Required knowledge includes:

  • Experience in executing flow cytometry experiments and/or single cell-based assays.
  • Assay development experience with excellent problem solving and troubleshooting abilities.
  • A proven understanding of analytical techniques such as flow cytometry, enzymatic activity assessment, immunoassays, and protein detection.


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