Endothelial Research Scientist

1 month ago


London, Greater London, United Kingdom University of Bristol Full time
Position Overview

This is a temporary role focused on conducting a study regarding the influence of lipoproteins on endothelial secretion.

Preliminary investigations have revealed a secretory mechanism influenced by elevated lipoprotein levels, and your task will be to finalize the mapping of the intracellular transport pathways involved, building upon prior findings.

Key Responsibilities

You will investigate the transport of fibronectin and other proteins within endothelial cells in response to lipoprotein exposure. Secretion levels will be quantified using ELISA, while the pathways will be delineated through cell imaging techniques utilizing confocal microscopy.

Your responsibilities will include the maintenance of endothelial cell cultures, organization of daily experimental tasks, meticulous data management, analysis of results, and preparation of manuscripts and figures for publication.

Qualifications

We invite applications from candidates who possess substantial experience in endothelial cell research and a proven track record in this field. The project requires expertise in protein biochemistry and cell biology.

Familiarity with mass spectrometry proteomics is essential, along with prior experience in investigating intracellular transport pathways through both biochemical and imaging methodologies.



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