Current jobs related to Lead Quantitative Pharmacologist - Cambridge, Cambridgeshire - Regeneron Pharmaceuticals, Inc
-
Senior Quantitative Pharmacologist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full timeJob Title: Senior Quantitative PharmacologistWe are seeking a highly skilled Senior Quantitative Pharmacologist to join our team at Regeneron Pharmaceuticals, Inc. The successful candidate will be responsible for providing significant contributions to the development of multiple programs through the execution of PK, PD, and other types of quantitative...
-
Senior Quantitative Pharmacologist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full timeJob Title: Senior Quantitative PharmacologistWe are seeking a highly skilled Senior Quantitative Pharmacologist to join our team at Regeneron Pharmaceuticals, Inc. The successful candidate will be responsible for providing significant contributions to the development of multiple programs through the execution of PK, PD, and other types of quantitative...
-
Pharmacologist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals Inc. Full timeJob Title: PharmacologistRegeneron Pharmaceuticals Inc. is seeking a highly skilled Pharmacologist to join our team.Job Summary:We are looking for a Pharmacologist to design and conduct quantitative or other pharmacometric analyses of a sophisticated nature to support our program development strategy. The successful candidate will be responsible for...
-
Pharmacologist
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals Inc. Full timeJob Title: PharmacologistRegeneron Pharmaceuticals Inc. is seeking a highly skilled Pharmacologist to join our team.Job Summary:We are looking for a Pharmacologist to design and conduct quantitative or other pharmacometric analyses of a sophisticated nature to support our program development strategy. The successful candidate will be responsible for...
-
Pharmacologist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals Inc. Full timeJob Title: PharmacologistRegeneron Pharmaceuticals Inc. is seeking a highly skilled Pharmacologist to join our team.Job SummaryWe are looking for a talented Pharmacologist to design and conduct quantitative or other pharmacometric analyses of a sophisticated nature. The successful candidate will be responsible for prospectively providing pharmacometric...
-
Pharmacologist
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals Inc. Full timeJob Title: PharmacologistRegeneron Pharmaceuticals Inc. is seeking a highly skilled Pharmacologist to join our team.Job SummaryWe are looking for a talented Pharmacologist to design and conduct quantitative or other pharmacometric analyses of a sophisticated nature. The successful candidate will be responsible for prospectively providing pharmacometric...
-
Senior Quantitative Pharmacologist
1 day ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeThis is an exciting opportunity to contribute to the development of model-informed drug development (MIDD) plans for assigned projects at Pfizer. The successful candidate will work closely with partners to optimize prospective studies, inform drug development strategy, and project decision-making.Key Responsibilities:Conduct and report quantitative analyses...
-
Senior Quantitative Pharmacology Expert
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full timeRegeneron Pharmaceuticals, Inc is seeking a highly skilled Senior Quantitative Pharmacologist to join our team. The ideal candidate will have a strong background in quantitative pharmacology and experience in designing, implementing, and analyzing pharmacokinetic and pharmacodynamic studies.Key ResponsibilitiesDesign and implement quantitative pharmacology...
-
Senior Quantitative Analyst
5 days ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob SummaryWe are seeking a highly skilled Senior Quantitative Analyst to join our team at Bicycle Therapeutics. As a key member of our drug discovery team, you will be responsible for developing and applying sound mathematical, statistical, and computational models to support our peptide discovery and pre-clinical development efforts.Key...
-
Senior Quantitative Analyst
1 week ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob SummaryWe are seeking a highly skilled Senior Quantitative Analyst to join our team at Bicycle Therapeutics. As a Senior Quantitative Analyst, you will play a key role in developing and applying sound mathematical, statistical, and computational models to support our peptide discovery and pre-clinical development efforts.Key ResponsibilitiesApply...
-
Pharmacometrician
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeJob SummaryThis position requires onsite/hybrid work in various Pfizer locations, including La Jolla, CA, South San Francisco, CA, Bothell, WA, NYHQ, NY, Cambridge, MA, and Groton, CT.Key ResponsibilitiesContribute to the development of model-informed drug development (MIDD) plans for assigned projects to optimize prospective studies and inform drug...
-
Pharmacometrician
3 weeks ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeJob SummaryThis position requires onsite/hybrid work in various Pfizer locations, including La Jolla, CA, South San Francisco, CA, Bothell, WA, NYHQ, NY, Cambridge, MA, and Groton, CT.Key ResponsibilitiesContribute to the development of model-informed drug development (MIDD) plans for assigned projects to optimize prospective studies and inform drug...
-
Pharmacometrician
1 month ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeJob SummaryThis position requires collaboration with cross-functional teams to develop model-informed drug development (MIDD) plans for assigned projects, optimizing prospective studies and informing drug development strategy.Key ResponsibilitiesConduct and report quantitative analyses integrating pharmacokinetics, pharmacodynamics, patient characteristics,...
-
Pharmacometrician
1 month ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeJob SummaryThis position requires collaboration with cross-functional teams to develop model-informed drug development (MIDD) plans for assigned projects, optimizing prospective studies and informing drug development strategy.Key ResponsibilitiesConduct and report quantitative analyses integrating pharmacokinetics, pharmacodynamics, patient characteristics,...
-
Quantitative Research Manager
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hasson Associates Recruitment Ltd Full timeAbout the RoleWe are seeking a highly skilled Quantitative Research Manager to join our team at Hasson Associates Recruitment Ltd. As a key member of our team, you will be responsible for leading quantitative research projects in the sustainability and food sectors.Key ResponsibilitiesDesign and execute quantitative research projects to meet client...
-
Quantitative Research Manager
2 weeks ago
Cambridge, Cambridgeshire, United Kingdom Hasson Associates Recruitment Ltd Full timeAbout the RoleWe are seeking a highly skilled Quantitative Research Manager to join our team at Hasson Associates Recruitment Ltd. As a key member of our team, you will be responsible for leading quantitative research projects in the sustainability and food sectors.Key ResponsibilitiesDesign and execute quantitative research projects to meet client...
-
Associate Director, DMPK
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob Title: Associate Director, DMPKJoin our team at Bicycle Therapeutics as an Associate Director, DMPK, and play a key role in driving the success of our drug discovery and development projects. As a senior leader in our Quantitative Pharmacology group, you will be responsible for representing DMPK and collaborating with drug discovery medicinal chemists...
-
Associate Director, DMPK
4 weeks ago
Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full timeJob Title: Associate Director, DMPKJoin our team at Bicycle Therapeutics as an Associate Director, DMPK, and play a key role in driving the success of our drug discovery and development projects. As a senior leader in our Quantitative Pharmacology group, you will be responsible for representing DMPK and collaborating with drug discovery medicinal chemists...
-
Cambridge, Cambridgeshire, United Kingdom Regeneron Pharmaceuticals, Inc Full timeSenior Director, Quantitative PharmacologyRegeneron Pharmaceuticals, Inc is seeking a highly skilled Senior Director, Quantitative Pharmacology to join our team. As a Senior Director in Pharmacometrics, this individual will be responsible for managing PMx support for a number of programs in one or more therapeutic focus areas of the development portfolio.Key...
-
Senior Biostatistician
1 week ago
Cambridge, Cambridgeshire, United Kingdom Pfizer Full timeROLE SUMMARYThis position will provide statistical support for projects in the Inflammation and Immunology disease area in Global Product Development. The qualified candidate will collaborate and work closely with project or study teams and provide statistical expertise in designing clinical trials, developing protocols, writing statistical analysis plans,...
Lead Quantitative Pharmacologist
2 months ago
We are seeking a Lead Quantitative Pharmacologist to play a pivotal role in advancing various programs. This position entails the execution of pharmacokinetic (PK), pharmacodynamic (PD), and other quantitative analyses that are crucial for the progression of these initiatives. The individual in this role will collaborate across departments to evaluate, design, select, and implement standardized scientific methodologies for analyzing both in-vivo and in-vitro pharmacokinetic and pharmacodynamic studies.
A typical day for a Lead Quantitative Pharmacologist may include:
- Collaborating with team members under moderate supervision to plan, design, implement, and analyze results for a variety of pharmacometric (PMx) studies.
- Conducting a wide range of quantitative PK or PK/PD analyses, including but not limited to non-compartmental analysis (NCA), compartmental modeling, population pharmacokinetics (PopPK), translational modeling, disease modeling, population PK/PD, and exposure-response analyses, often in close collaboration with Research Specialists or the PMx Statistics Programming team to deliver PMx results.
- Working alongside PMx Research Specialists, PMx Programming Team, Scientific Writers, and other contributors to prepare tables, figures, and listings (TFLs) in support of various internal or regulatory documents such as PK/PD study reports, Investigational New Drug (IND) applications, Clinical Trial Applications (CTA), and summary modules for Clinical Study Reports (CSR) and Investigator's Brochures (IB).
- With guidance from senior PMx staff, assisting in the preparation of materials for regulatory interactions, including PMx materials for regulatory background packages for pre-IND, End-of-Phase 2 (EOP2), and pre-BLA meetings, and performing additional analyses as necessary to support these interactions.
This role may be a good fit for you if:
- You possess strong interpersonal and communication skills, both written and verbal, and can work independently.
- You are familiar with regulatory and research guidelines pertaining to drug development, such as ICH and GxP guidelines.
- You seek to work in an environment that values data integrity.
- You are prepared to make independent decisions for assigned studies or indications while proactively seeking management input when necessary to ensure successful outcomes.
To be considered for this position, you must:
- Hold a PhD and have a minimum of 3 years of relevant experience.
- Demonstrate an advanced understanding of quantitative concepts and techniques, including non-compartmental analysis methods, compartmental modeling, translational pharmacology, exposure-response analysis methods, nonlinear mixed-effects modeling, and disease modeling/quantitative systems pharmacology (QSP).
- Have experience with advanced pharmacometric statistical methods applicable to clinical trials, such as survival analysis, stratified or covariate analyses, strategies for handling missing data, logistic regression, survival analysis, and Bayesian approaches.
