Senior Scientist

3 weeks ago

Slough, Slough, United Kingdom Lonza Group Ltd. Full time
Senior Scientist - Mammalian Cell Biology

Lonza Group Ltd. is a global leader in life sciences, operating across three continents. We're seeking an experienced cell biologist with extensive knowledge of mammalian cell cycle, metabolism, signaling pathways, and CHO cell biology to join our team of experts in Cell Culture Media Development as a Lead Scientist.

Key Responsibilities:

  • Collaborate with the Head, Media R&D Slough, to plan and prioritize tasks and assignments in a work program.
  • Be a subject matter expert in cell line development and support the project team.
  • Lead and execute projects on mammalian cell line development, ensuring all quality and regulatory aspects are fulfilled.
  • Design and execute experimental plans, analyze experimental data, and write technical reports.
  • Ensure that studies are scientifically sound and in line with current regulatory guidance and expectations.
  • Contribute scientific expertise and propose new ideas and product concepts targeting the research market, drawn from scientific literature and personal experience.
  • Ensure GLP and EHS regulations are followed.
  • Perform other duties as assigned.

Key Requirements:

  • Minimum of BSc in Biotechnology / Biochemistry or other related fields (MSc desirable).
  • Technical background in mammalian cell line development and experience of basic cell biology techniques, i.e. mammalian cell culture, flow cytometry, transfection, cryopreservation, clonal isolations, etc. is highly desirable.
  • Knowledge of CHO cell biology, cell cycle regulation, CHO cell metabolism is highly desirable.
  • Experience with high-throughput small scale bioreactors, i.e. ambr15, ambr250 is advantageous.
  • Good understanding of upstream processes, including fed-batch and perfusion cultures.
  • Knowledgeable of the current best practices for developing cell culture media, including metabolomics, metabolic flux analysis is advantageous.
  • Strong interpersonal, presentation, time management, organizational, and written/oral communication skills are highly desirable.
  • Previous experience working in cross-matrixed/functional teams and ability to work on complex projects effectively and collaboratively in a matrixed environment is an asset.
  • Ability to successfully complete complex projects will be viewed favorably.
  • Inventiveness, enthusiasm, motivation, and problem-solving skills to develop new technical capabilities and solve challenging problems are assets.

We respect and protect our people and our environment. Any success we achieve is no success at all if not achieved ethically. People come to Lonza for the challenge and creativity of solving complex problems and developing new ideas in life sciences. In return, we offer the satisfaction that comes with improving lives all around the world.

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