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Protein Design Specialist

2 months ago

London, Greater London, United Kingdom Baseimmune Full time
About the Role

We are seeking an experienced Computational Protein Design specialist to join our Antigen Design team at Baseimmune. As a key member of our team, you will be responsible for driving the development of computational pipelines that use AI techniques to create proteins for use as vaccine antigens.

Key Responsibilities
  • Develop and implement computational pipelines for protein design, leveraging deep learning methodologies and generative AI.
  • Collaborate with laboratory teams to validate and benchmark newly implemented methodologies using in silico, in vitro, and in vivo models.
  • Apply computational-based pipelines and structural expertise to design proteins presenting target epitopes in desired conformations.
  • Analyse and interpret experimental data to advance the design process.
Requirements
  • Ph.D. in Structural Biology, Biophysics, Computational Biology, Biochemistry, or a related field.
  • Minimum of 4 years' experience in computational protein design within an academic or industry setting.
  • Extensive knowledge of statistical and deep learning methods applied to protein design, such as RFdiffusion, MPNN, AlphaFold, and Rosetta.
  • Experienced programming in Python and Linux command line.
  • Proven track record of scientific innovation and publications in reputable journals.
What We Offer
  • Competitive starting salary
  • Private medical health insurance
  • Opportunities for career growth and professional development
  • 26 days holiday leave + bank holidays
  • Enhanced sick pay
  • Pension plan

Baseimmune is an equal opportunity employer and values diversity and inclusion in our workplace. We do not provide visa sponsorship for this position.