Collaborate with the Functional Genomics Screening Laboratory

1 month ago


Swindon, Swindon, United Kingdom NERC - the Natural Environment Research Council Full time
Opportunity Overview

The Functional Genomics Screening Laboratory (FGSL) is a joint venture between the MRC, AstraZeneca, and the Milner Therapeutics Institute, University of Cambridge. This initiative aims to provide UK-based academic groups and, where space allows, UK-based small and medium-sized enterprises and industry, with access to a state-of-the-art arrayed functional genomics screening laboratory.

Job Description

We are seeking a researcher to collaborate with the FGSL on projects using complex human in vitro models for CRISPR screening. The successful candidate will work with the FGSL to define the purpose of the screen and desired outcomes, and will contribute to the development of new human in vitro models.

Key Responsibilities
  • Collaborate with the FGSL on CRISPR screening projects
  • Contribute to the development of new human in vitro models
  • Define the purpose of the screen and desired outcomes
  • Work with the FGSL to design and execute CRISPR screens
Requirements
  • Eligibility for MRC funding
  • Experience with CRISPR screening and human in vitro models
  • Strong communication and collaboration skills
How to Apply

To apply, please submit an application form through the FGSL website. The application form should include details about the proposed project, including the in vitro model, desired screen, and endpoint assay. Please also include any additional information requested in the application form.

Assessment Process

The FGSL has a Joint Steering Committee (JSC) to oversee the laboratory. The JSC has the final decision regarding which applications are accepted for screens and how they are funded. The JSC will assess applications based on the following criteria: in vivo recapitulation and translatability of biological model, availability and scalability of the cell model, feasibility of assay endpoint for screening, assay controls available, and gene editing feasibility of the cell model.



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