Head of Translational Medicine

1 month ago


Cambridge, Cambridgeshire, United Kingdom Sarepta Therapeutics Full time
Unlock the Potential of Genetic Medicine

Sarepta Therapeutics is at the forefront of genetic medicine, and we're seeking a highly skilled professional to join our team as the Head of Translational Medicine. This role will play a critical part in driving our translational medicine initiatives, particularly focusing on the integration of imaging biomarkers into our development programs.

Key Responsibilities:
  • Oversee the translational medicine initiatives, ensuring the effective application of innovative imaging techniques to enhance our understanding of therapeutics efficacy.
  • Collaborate closely with cross-functional teams to align translational medicine goals with overall development objectives.
  • Drive reverse translation by leveraging clinical trial data to inform preclinical research, particularly focusing on mechanism studies and hypothesis testing.
  • Provide scientific leadership in the application of MRI technology for muscle and cardiac imaging within the context of biomarker discovery and development.
  • Develop and implement strategies to incorporate advanced imaging biomarkers into clinical protocols, ensuring alignment with regulatory and clinical endpoints.
  • Oversee the design and execution of preclinical and clinical studies involving imaging biomarkers, ensuring high standards of scientific rigor and data quality.
  • Act as a scientific and strategic liaison with external partners, including key opinion leaders and regulatory bodies, to drive the successful implementation of imaging technologies in drug development.
  • Identify and champion novel imaging techniques and digital biomarkers that can be integrated into the drug development process to enhance patient selection, treatment monitoring, and therapeutic outcomes.
Requirements:
  • MD or PhD in a relevant field such as Radiology, Medical Imaging, or Biomedical Sciences.
  • A minimum of 11+ years of experience in the biopharma or biotechnology industry or relevant academic experience, with a proven track record in translational medicine or imaging biomarker development.
  • Extensive experience in MRI technology with a strong focus on muscle and cardiac imaging.
  • Strong understanding of the regulatory landscape and experience in preparing and submitting regulatory documents.
  • Excellent communication and leadership skills, with the ability to influence and drive projects forward in a fast-paced environment.

Sarepta Therapeutics offers a competitive compensation and benefit package. This position is hybrid, with a mix of on-site and remote work. We're committed to maintaining a culture that acknowledges the importance of work-life balance and provides opportunities for professional growth and development.



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