Laboratory Technician
3 days ago
We are seeking a highly skilled and motivated Laboratory Technician to join our team at Great Ormond Street Hospital for Children NHS Foundation Trust. As a Laboratory Technician, you will play a critical role in supporting the manufacture of advanced therapy medicinal products (ATMPs) for the treatment of childhood diseases.
Key Responsibilities- Contribute to the optimisation and validation of GMP manufacturing processes applicable to ATMP clinical trials
- Participate in the manufacturing of ATMP products for clinical trials
- Validate QC tests relevant to ATMP manufacture
- Write and implement new BMRs, SOPs, and worksheets
- Accurately complete GMP documentation related to manufacturing, storage, and shipment of ATMPs
- Ensure compliance with UK MHRA GMP and GCP regulations applying to ATMP manufacturing and conduct of first-in-human clinical trials
- Contribute to the overall normal activities of the research team and department as required, including laboratory duties and attendance at departmental meetings
- BSc in Medical Laboratory Science or completion of STP training programme or equivalent
- Experience of working in a CPA/UKAS accredited laboratory or other related translational laboratory
- Understanding of the structure of a Pharmacy Quality System for manufacture under an MHRA license
- Experience of writing and following BMRs, SOPs, and other key manufacturing documents
- Experience in GMP manufacturing
- Experience in the manufacture of ATMPs
- Experience in culture and/or manipulation of human primary cells and cell lines
We offer a competitive salary and benefits package, as well as opportunities for professional development and growth. If you are a motivated and experienced Laboratory Technician looking for a new challenge, please apply today.
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