Laboratory Technician

3 days ago


London, Greater London, United Kingdom Great Ormond Street Hospital for Children NHS Foundation Trust Full time
About the Role

We are seeking a highly skilled and motivated Laboratory Technician to join our team at Great Ormond Street Hospital for Children NHS Foundation Trust. As a Laboratory Technician, you will play a critical role in supporting the manufacture of advanced therapy medicinal products (ATMPs) for the treatment of childhood diseases.

Key Responsibilities
  • Contribute to the optimisation and validation of GMP manufacturing processes applicable to ATMP clinical trials
  • Participate in the manufacturing of ATMP products for clinical trials
  • Validate QC tests relevant to ATMP manufacture
  • Write and implement new BMRs, SOPs, and worksheets
  • Accurately complete GMP documentation related to manufacturing, storage, and shipment of ATMPs
  • Ensure compliance with UK MHRA GMP and GCP regulations applying to ATMP manufacturing and conduct of first-in-human clinical trials
  • Contribute to the overall normal activities of the research team and department as required, including laboratory duties and attendance at departmental meetings
Requirements
  • BSc in Medical Laboratory Science or completion of STP training programme or equivalent
  • Experience of working in a CPA/UKAS accredited laboratory or other related translational laboratory
  • Understanding of the structure of a Pharmacy Quality System for manufacture under an MHRA license
  • Experience of writing and following BMRs, SOPs, and other key manufacturing documents
  • Experience in GMP manufacturing
  • Experience in the manufacture of ATMPs
  • Experience in culture and/or manipulation of human primary cells and cell lines
What We Offer

We offer a competitive salary and benefits package, as well as opportunities for professional development and growth. If you are a motivated and experienced Laboratory Technician looking for a new challenge, please apply today.



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