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Associate Director of Drug Metabolism

2 months ago


Cambridge, Cambridgeshire, United Kingdom Bicycle Therapeutics Full time
Job Description

Bicycle Therapeutics is a clinical-stage biopharmaceutical company seeking a highly skilled Senior DMPK Scientist or Associate Director of Drug Metabolism to join our team. As a key member of our Quantitative Pharmacology group, you will be responsible for representing DMPK and designing non-clinical studies to support multiple projects from target identification through to candidate selection and regulatory submission.

Key Responsibilities:
  • Design and Implement DMPK Strategy: Develop and execute DMPK strategies for multiple projects, ensuring alignment with project goals and timelines.
  • Lead DMPK Activities: Oversee DMPK activities, including interactions with external CROs and internal project stakeholders, to ensure seamless project execution.
  • Collaborate with Cross-Functional Teams: Work closely with in-vivo pharmacology, toxicology, and clinical pharmacology teams to design experiments and understand preclinical PK/PD relationships.
  • Track DMPK Budgets: Monitor and manage DMPK budgets for CROs and contribute to project spending forecasts.
Requirements:
  • Education: MSc/PhD in a relevant scientific discipline, such as drug metabolism, pharmacology, or pharmaceutical sciences.
  • Experience: Proven track record of problem-solving and successful delivery in DMPK drug discovery and/or development projects.
  • Skills: In-depth understanding of DMPK science, with additional knowledge of related disciplines. Excellent organization and communication skills, with the ability to influence and adapt to different cultures and partner expectations.
What We Offer:
  • State-of-the-art Campus Environment: Work in a modern, on-campus facility with access to cutting-edge resources and amenities.
  • Flexible Working Environment: Enjoy a flexible work environment that supports work-life balance and collaboration.
  • Competitive Rewards: Receive a competitive salary, annual company bonus, and comprehensive benefits package.

Bicycle Therapeutics is committed to building a diverse workforce that is representative of the communities we serve. We recognize that diverse and inclusive teams build a stronger and more innovative company. Therefore, all qualified applicants will be considered for employment, and we do not discriminate on the basis of race, religion, color, gender, sexual orientation, age, disability status, marital status, or veteran status.