Scientific Director

4 weeks ago


London, Greater London, United Kingdom Biopretium Full time
Job Title: Director, Modelling & Simulation

Location: Remote in the UK. Occasional need to be in the office in the North East or Berkshire.

About Biopretium

Biopretium have been retained by a drug development and manufacturing business providing integrated programs and tailored services across the entire development pathway. They partner with pharmaceutical and biotech companies to accelerate their drug development processes and ultimately get treatments to patients more quickly.

About the Role

As a key member of Biopretium's Scientific Consulting team, you will provide leadership for the Modelling and Simulation (M&S) team, managing resources to deliver customer projects meeting time, budget and quality criteria. You will drive customer adoption of M&S activities, working with the commercial team to promote their scientific capabilities and secure new standalone and integrated programs of work.

Key Responsibilities
  • Perform hands-on modelling and simulation (M&S) scientific support and input throughout the project lifecycle (design, planning, delivery and reporting) to ensure client's study objectives are achieved.
  • Manage M&S team, ensuring availability of sufficient resources and capabilities for delivery of project work to agreed timelines and budget.
  • Work with the commercial and marketing team to promote service offerings in the marketplace via appropriate channels and materials, including website, factsheet, scientific publications and conference attendance.
  • Provide scientific support to effectively communicate the company's modelling capabilities and offerings in customer discussions.
  • Perform hands-on PBPK M&S activities to deliver customer projects where necessary.
  • Produce high quality reports which clearly present and summarise M&S project findings.
Requirements

The successful applicant will be degree qualified, ideally with a PhD with significant practice experience in building and applying physiologically based pharmacokinetic (PBPK) models across a range of applications, ideally utilising GastroPlus. Significant experience in biopharmaceutics, PK data analysis and modelling, metabolism and clinical pharmacology with an ability to relate a compound's in vitro physchem/biopharm/DMPK properties to preclinical and clinical in vivo performance.


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