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Laboratory Technical Specialist
4 months ago
We are a world class research-intensive university. We deliver teaching and learning of the highest quality. We play a leading role in economic, social and cultural development of the North East of England. Attracting and retaining high-calibre people is fundamental to our continued success.
What’s in it for you? Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.
Newcastle is an inclusive global University community where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.
**Salary**: £27,131 to £28,762 with progression to £31,411 per annum
**Closing Date**: 20 January 2023
The Role
An exciting opportunity has arisen for an experienced Technician to join our team. You will play a key role in delivering key capacities developed as part of our National Institute for Health Research Biomedical Research Centre in Ageing and Age-Related Conditions.
You will also spend 50% of your time working on an MRC-funded study investigating glial cell activity in dementia. In particular, you will be responsible for contributing to human tissue-based technical platforms for dementia research, including post-mortem tissue imaging and culturing of brain tissue derived from neurosurgical patients. A major focus of the role is to perform autoradiographical studies of post-mortem human brain tissue, which will be augmented with immunofluorescent analysis, standard immunohistochemistry and other techniques such as Western blotting. The remaining 50% of your time you will support the NIHR Newcastle Biomedical Research Centre, which recently received £23.1M funding from the National Institute of Healthcare Research to continue its world-leading research in ageing and multiple long-term conditions (Supervisor: Dr Daniel Erskine).
This position requires a capacity and willingness to learn new laboratory techniques, enthusiasm for dementia research, attention to detail and a strong desire to perform technical work to a high standard, excellent record-keeping, and the ability to work well with others as part of a multi-disciplinary team.
This post is full time tenable until January 2027
Key Accountabilities
- Consolidate or develop skills in the preparation of post-mortem human brain tissue, including cutting using a crytostat or microtome
- Consolidate or develop skills in performing autoradiography-based analysis of human brain specimens
- Perform histological and immunohistochemical staining of human brain specimens and cultured cells
- Perform Western blotting
- Prepare tissues for RT-pPCR
- Assist with the maintenance of cultured human cells and brain tissues
- Manage equipment and reagent inventories, taking responsibility for sourcing and ordering replacements
- Establish and maintain a safe/compliant working environment
- Assist with the completion and updating of a wide range of safety paperwork
- Oversee compliance tasks ensuring timely completion and maintenance of appropriate records
- Complete accident reporting and assist with investigations
- Maintain in-depth and up-to-date health and safety knowledge relevant to the specialism
- Organize and facilitate progress meetings
- Support researchers through the preparation of brain tissues for analysis to contribute to the wider research environment
- Assist managers with the identification of training and development needs
- Maintain specialist knowledge and skills, sharing with others
- Mentor junior staff, including students, and take responsibility for training junior staff and overseeing their laboratory work
- Maintain timesheets recording
The Person (Essential)
Knowledge, Skills and Experience
- Demonstrable work experience in a relevant technical role
- Proven capacity to develop new practical skills
- Thorough working knowledge of Health and Safety procedures
- Excellent team working skills
- Demonstrates practical abilities working in a laboratory environment
- Experience of performing autoradiography (Desirable)
- Experience of the safe and ethical handling of post-mortem human tissues (Desirable)
- Experience in cutting pathology specimens using a cryostat or microtome (Desirable)
Attributes and Behaviour
- Positive attitude to work
- Tact, diplomacy and able to handle difficult situations
- Ability to meet deadlines with effective time and resource management
- Clear communicator and active listener
- Consistent and appropriate approach to staff and situations
- Use of feedback for process improvement and staff development
- Team player, self starter and able to manage complex workload
- Ability to respond enthusiastically and positively to undergraduate students
**Qualifications**:
- BTEC HNC / HND; or A’ level (or equivale
