Bioanalytical Associate Principal Scientist

3 weeks ago

Little Chesterford, United Kingdom Domainex Full time

Are you a knowledgeable bioanalytical senior scientist or associate principal scientist who has an excellent understanding of protein analysis by mass spectrometry? Are you now looking for an exciting new challenge? If so, we have a fantastic opportunity to join the expanding bioanalytical team here at Domainex, a multi-award winning integrated drug discovery contract research organisation.

**What Is This Job All About?**

You will be part of a small team of bioanalytical scientists, contributing to the team's relevant projects and activities, collaborating closely to ensure the successes of your team.

You will spend your time developing and running in-tact and bottom-up analysis of large molecules by LC-MS and will proactively seek out solutions to bioanalytical problems.

You will work closely with the other business disciplines of Biology and Chemistry to develop strong working relationships and future true partnerships across projects and teams.

**What Are We Looking for In This Exciting New Role?**

When you join Domainex we will be looking for you to have the ability to
- Operate, maintain and trouble shoot Waters triple quadrupole and Q-TOF instruments.
- Perform intact analysis of large molecules, peptide mapping for characterisation of proteins and bottom-up quantitation of large molecule biomarkers.
- Apply, evaluate and interpret scientific theories, concepts, techniques and new technologies in bioanalytical mass spectrometry to support early-stage drug discovery.
- Interact with and present data to current and prospective clients.

**What Educational Background Are We Expecting?**

BSc/MSc in chemistry/biochemistry or related analytical discipline with ideally 5 years’ experience within a bioanalytical LC-MS/MS setting, ideally in a research environment, or a relevant PHD with 2 years’ experience.

**What Experience Will You Have?**
- Proven experience of developing intact and bottom-up LC-MS methods for large molecules.
- Extensive experience troubleshooting bioanalytical assays and LC-MS methodology, ideally with both QQQ and QTOF instruments.
- Experience in performing/developing various sample extraction/purification techniques including proteolytic digestion, immunopurification and SPE.
- Proficient at processing and interpreting complex bioanalytical data sets as well as producing high quality reports.
- Experience in native mass spectrometry and/or affinity selection mass spectrometry would be beneficial.
- Experience in mass spectrometry based high throughput screening would be beneficial.

**What Can We Offer You?**
- A competitive salary which will be determined by your qualifications and your experience.
- 25 days holiday plus bank holidays and you can choose to buy up to 10 days or sell up to 5 days per year plus a day off for your birthday each year.
- A generous pension scheme - Domainex will contribute 10% of your salary when you put 5% into our company scheme.
- A heavily discounted private medical insurance plan available for you and your family members.
- A group life assurance cover scheme of four times your salary.
- An excellent 24/7 confidential Employee Assistance Programme.
- A heavily discounted electric car scheme managed by the award-winning Octopus Energy.
- Significantly discounted gym membership for you and family members.
- Sustainability options including cycle to work, discounted bus travel and a lift share scheme.

We are based on the Chesterford Research Park just outside the charming market town of Saffron Walden, fifteen miles from the beautiful city of Cambridge. Chesterford Research Park has fabulous facilities including a restaurant, a gym, a seven-hole golf course and woodland walks. Close by is the main line railway station of Great Chesterford with a direct train line between Cambridge and London. There is a discounted shuttle service provided to and from the research park from the station.

  • Bioanalytical Associate Principal Scientist

    2 weeks ago

    Little Chesterford, United Kingdom Domainex Full time

    Are you a knowledgeable bioanalytical senior scientist or associate principal scientist who has an excellent understanding of protein analysis by mass spectrometry? Are you now looking for an exciting new challenge? If so, we have a fantastic opportunity to join the expanding bioanalytical team here at Domainex, a multi-award winning integrated drug...

  • Histology Scientist

    2 weeks ago

    Little Chesterford, United Kingdom Prestige Appointments Full time

    _We set science in motion to create a better world and have done so for over 100 years._Through our diverse and passionate global workforce of 14,000+ professionals - we've become a trusted provider of mission-critical products and services to customers in the biopharma, healthcare, education & government, and advanced technologies & appliedmaterials...

  • Research Associate

    2 weeks ago

    Little Chesterford, United Kingdom Isogenica Ltd Full time

    Research Associate (Alliances)Job Ref:RA2202Contract type: PermanentReports To: Senior Scientist or aboveTHE ROLEFor more than twenty years, Isogenica has built deep expertise and knowledge about how to find VHH antibodies and develop them into drugs in partnership with some of the world's most innovative biopharma companies. As a Research Associate in...

  • Kitchen Porter

    2 weeks ago

    Little Walsingham, United Kingdom WCTA Ltd Full time

    Working in the kitchen environment, your principle duties will be to keep all areas of the kitchen clean and tidy including walk in fridges and freezers, putting away orders as delivered insuring that oldest deliveries are used first. Completing all relevant paperwork including cleaning schedules and delivery monitoring. The postholder must be a flexible...

  • Site Manager

    1 month ago

    Little Thurrock, United Kingdom Berkshire Talent Partnership Full time

    Berkshire Talent Partnership are searching for a contract Site Manager to deliver a Battery Energy Storage plant in Thurrock and also spend time on other projects throughout the UK to support completions activities. Hit Apply below to send your application for consideration Ensure that your CV is up to date, and that you have read the job specs first.This is...

  • Senior Project Cost Estimator

    4 weeks ago

    Little Stanney, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that people...

  • Senior Estimator

    4 weeks ago

    Little Stanney, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that...

  • Senior Drafter

    4 weeks ago

    Little Driffield, United Kingdom Tempest Jones Recruitment Full time

    Senior Draughtsperson - Power SectornUK (Hybrid or Fully Remote Working)nSalary to £35k + competitive benefits packageOur client is a leading consultancy who provide engineering and professional planning services to the power sector. They specialise in the design and survey of Overhead Lines, Underground Cables, and Substation Systems for major power...

  • Support Worker

    3 weeks ago

    Little Chalfont, United Kingdom Appcastenterprise Full time

    **Location -White Lion Road, Amersham** **About Us Hightown is a charitable housing association operating principally in Hertfordshire, Bedfordshire, Berkshire and Buckinghamshire. We believe everyone should have a home and the support they need, so our aim is to build new homes and to provide excellenthousing and support. We currently manage over 8,000...

  • Support Worker

    4 weeks ago

    Little Chalfont, United Kingdom Hightown Housing Association Full time

    **Location -White Lion Road, Little Chalfont, Amersham** **About Us** Hightown is a charitable housing association operating principally in Hertfordshire, Bedfordshire, Berkshire and Buckinghamshire. We believe everyone should have a home and the support they need, so our aim is to build new homes and to provide excellent housing and support. We currently...

  • Senior Drafter

    3 weeks ago

    Little Driffield, East Yorkshire, United Kingdom Tempest Jones Recruitment Full time £35,000

    Senior Draughtsperson - Power SectorUK (Hybrid or Fully Remote Working)Salary to £35k + competitive benefits packageOur client is a leading consultancy who provide engineering and professional planning services to the power sector. They specialise in the design and survey of Overhead Lines, Underground Cables, and Substation Systems for major power...

  • Senior Project Cost Estimator

    1 month ago

    Little Stanney, Cheshire, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that...

  • Senior Project Cost Estimator

    1 month ago

    Little Stanney, Cheshire, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that...

  • Senior Drafter

    2 weeks ago

    Little Driffield, East Yorkshire, United Kingdom Tempest Jones Recruitment Full time £35,000

    Senior Draughtsperson - Power SectorUK (Hybrid or Fully Remote Working)Salary to £35k + competitive benefits packageOur client is a leading consultancy who provide engineering and professional planning services to the power sector. They specialise in the design and survey of Overhead Lines, Underground Cables, and Substation Systems for major power...

  • Support Worker

    2 weeks ago

    Little Chalfont, Buckinghamshire, United Kingdom Hightown Housing Association Full time

    Location -White Lion Road, AmershamAbout UsHightown is a charitable housing association operating principally in Hertfordshire, Bedfordshire, Berkshire and Buckinghamshire. We believe everyone should have a home and the support they need, so our aim is to build new homes and to provide excellent housing and support.We currently manage over 8,000 homes and...

  • Senior Estimator

    1 month ago

    Little Stanney, Cheshire, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that...

  • Senior Estimator

    1 month ago

    Little Stanney, Cheshire, United Kingdom Bloor Homes - Commercial Full time

    Senior Estimator Want to make an application? Make sure your CV is up to date, then read the following job specs carefully before applying. When registering to this job board you will be redirected to the online application form. Please ensure that this is completed in full in order that your application can be reviewed. At Bellway we recognise that...