Development Scientist

4 weeks ago


Oxford, United Kingdom Oxford Nanopore Technologies Full time

Oxford Nanopore's sequencing platform is the only technology that offers real-time analysis (for rapid insights), in fully scalable formats from pocket to population scale, that can analyse native DNA or RNA and sequence any length of fragment to achieveshort to ultra-long read lengths.

Our goal is to enable the analysis of any living thing, by anyone, anywhere. We offer real-time nanopore-based DNA/RNA sequencing technology: accessible, easy to use and fully scalable for any requirement

We are looking for a highly motivated individual to join the Biologics Development team as a Development Scientist with a responsibility to develop novel sequencing chemistries through design of multifaceted biologics components and testing on our platform.

The details:
We continuously strive to improve and upgrade our sequencing chemistries as well as adding novel functionalities to our platform. Working within a highly multi-disciplinary team this primarily lab based role will be focused on the design and improvement ofnovel sequencing chemistry solutions. This includes iterative improvement of established chemistries through biochemical and molecular biology tools through to in depth analysis of electrophysiology experiments.

The role will involve:

- Developing multiple sequencing chemistry schemes through assessment on our nanopore sensing platform
- Design and test improvements to sequencing adapters, enzymes, nanopores and sample preparation to enable novel functionalities
- Carrying out experiments on our platform to drive improvement in sequencing chemistry performance metrics
- Preparing clearly articulated experimental reports and data presentations whilst maintaining well organised records
- Communicating with internal and external collaborators including senior management

What we're looking for...
We'll expect you to have a PhD in Biochemistry, molecular biology, biophysics or related field with several years of postdoctoral experience.

Experience with protein mutagenesis for improved function, DNA-protein complexes and membrane proteins / nanopores would all be beneficial as well as a practical knowledge and self-sufficiency in analysis of large complex datasets would be advantageous.

You will have an opportunity to utilise your skills to make a real contribution towards the next disruptive technology in a global organisation while maintaining its start-up culture.

Applications are encouraged from highly motivated individuals who enjoy taking on new challenges, are quickly adaptable in an exciting and fast-paced environment, and who perform well under pressure.

We offer outstanding benefits to include an attractive bonus, generous pension contributions, private healthcare and an excellent starting salary.

Based within beautiful, landscaped surroundings with tree-lined walks, water features and a lake, all of which make for a wonderful working environment.

LI-JC1



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