Associate Principal Scientist

**Key Roles and Responsibilities**:

- Conduct human PK, dose predictions and using routine approaches and including PBPK as appropriate using available software
- Collate and interpretation of results from the PK and ADME teams within the Pharmaron organization and further analyse/model/simulate in the context of the project aims.
- Ensure the smooth operation and scheduling of the DMPK screening strategy for the matrix drug discovery teams internal to PDDSE and external with clients.
- Maintenance and presentation of IVIVE and SAR for ADME properties to high standard.
- Provide quality data, written reports and presentations internally and to our partners to ensure regular progress updates and client satisfaction.
- Able to act as point of contact and manage client interactions for specified parts of an integrated project
- The role requires meticulous attention to detail and for all work to be conducted strictly in accordance with company Policies and Procedures and Standard Operating Procedures.

**Essential Requirements**:

- BSc or higher in relevant scientific discipline, pharmacology, pharmaceutical sciences
- Experience of working in DMPK drug discovery and/or development projects with appreciation of related disciplines
- Working knowledge of multiple DMPK/ADME assays

**Why Should You Apply?**
- This is an opportunity for you as a successful DMPK scientist to: make an even higher impact in the scientific field, be a highly valued member of our team and have a real impact in a fast-growing and highly respected CRO striving to become the world leader in contract research services.
- Build and shape your career in an environment that sets and commits to the highest standards of scientific research.
- To be part of a team who support each other, embrace and solve technical challenges and put excellence at the heart of all that we do.

**We offer**:

- **Vibrant and dynamic employment - **we are a highly specialised, growth company operating in a critical sector of the economy - our future is strong and exciting
- **Opportunities to develop your skills and yourself - **our rapid growth brings greater opportunities for you to learn and grow faster
- **A great team where we all support each other - **enjoy your work - after all you spend about a third of your time here

**Our Company**:"We are a dynamic, fast-growing company, with an enviable reputation for leading edge science, offering contract research services to some of the world's leading pharmaceutical companies, solving what were believed to be unsolvable scientific challenges".

We believe in our ability to relentlessly push forward the boundaries of scientific excellence, delivering solutions for our clients, always operating ethically and with integrity. We take pride in our professionalism and commitment to always deliver our very best work.

We are based in Hertfordshire, in the town of Hoddesdon. The Hoddesdon campus, consisting of several purpose built scientific and administrative buildings together with a purpose built conference STE area has more than 5,000m2 of premier R&D space and houses an established Process Chemistry, Analytical Chemistry and Drug Discovery team, and a newly formed Formulation Development department. The Hoddesdon site has state-of-the-art Good Manufacturing Practice (GMP) standard facilities for the development of Active Pharmaceutical Ingredients (API), formulation development and process chemistry. We offer our employees a highly supportive team-work environment, enabling them to develop and liberate their true potential.
- Pharmaron is a premier R&D service company supporting the life sciences industry. Founded in 2004, Pharmaron has invested in its people and facilities having established diverse drug R&D service capabilities, ranging from synthetic, medicinal and analytical chemistry, biology, DMPK, pharmacology, drug safety assessment, radiochemistry and isotopically labelled metabolism, chemical & pharmaceutical development to clinical development. With operations in China, US and UK staffed by over 19,000 employees, Pharmaron has an excellent track record in the delivery of R&D solutions to its partners in North America, Europe, Japan and China._

Schedule:

- Day shift
- Monday to Friday

Work Location: In person