Associate Director/director Early-stage Formulation
6 months ago
**Associate Director/Director Early-Stage Formulation Science**
**Cambridge**
**Competitive Salary & Benefits**
**Make a more meaningful impact to patients’ lives around the globe**
With our ground-breaking pipeline, the outlook is bright. Be proud to be part of a place that has achieved so much yet is still moving forward. There’s no better time to join our global, growing enterprise as we lead the way for healthcare and society.
An exciting bioscience hotspot, Cambridge is home to one of AstraZeneca’s three strategic, global R&D Centres, alongside Gothenburg and Gaithersburg. Over 3,600 employees are based in Cambridge. Our offices are internationally renowned for attracting high performers, including several Nobel prize winners.
Be part of a dedicated Research & Development team. Fuelled by our commitment to help more patients, strengthen our pipeline, and grow our area.
You will be accountable for the performance and results across team(s) within the area of Biopharmaceutical science. Setting departmental objectives/plans to ensure delivery of business objectives. Responsible for establishing, advising, and providing strategic, tactical and scientific leadership to the Bioanalytical area.
The Biopharmaceutical Development (BPD) group is a multi-disciplinary scientific function providing expertise in Process/Analytical/Formulation/Device Development and Characterization with integrated Bioprocess Engineering, Clinical Manufacturing, and Supply Chain and Logistics operations. The group is also responsible for transferring the processes to different clinical and commercial sites in and outside the AstraZeneca organization. BPD group is present in multiple sites in the US and the UK.
**What you’ll do**
- Provide scientific and strategic leadership for protein formulation and Drug Product development.
- Lead cross-functional teams in a matrix organisation including science & technology, Drug Product, and CMC teams.
- Active engagement in external science through publications, conferences, and relevant scientific forums to support growth of a strong scientific culture.
**Essential Criteria**
- BS, MS or PhD of relevant experience. Degree should be in Chemical/biochemical engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or related field.
- Proven leadership track record.
- Scientific leader in parenteral protein formulation development from pre-clinical to Ph3 clinical studies.
- Scientific expert in protein characterisation (e.g., high concentration formulations).
- Experience with developability assessment of complex protein modalities (e.g., mAbs, bispecifics, antibody fusions, ADC’s, T-cell engagers) to support CMC development knowledge of predictive tools for protein development (e.g. in-silico and structural modelling, machine learning tools).
- Experience with combination product development.
- Science orientated, highly motivated individual with drive to succeed.
- Excellent communication skills, strong interpersonal skills, and ability to thrive in an interdisciplinary fast paced environment.
At AstraZeneca, we 're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth and development.
**So, what’s next?**
**Where can I find out more?
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