Ktp Associate in Antimicrobial Drug
1 month ago
**Salary**: £37,500 (plus substantial training budget)
Newcastle University is a great place to work, with excellent benefits. We have a generous holiday package; plus the opportunity to buy more, great pension schemes and a number of health and wellbeing initiatives to support you.
**Closing Date**: 30 November 2023
The Role
**Salary**: £37,500 (plus substantial training budget)
Based at Bicycle TX, Cambridge you will help to achieve a Knowledge Transfer Partnership’s objective to transfer key knowledge and techniques required to develop novel antibiotics.
**Benefits**: Develop managerial skills and attend two residential managerial workshops (each of one week duration) £6,000 personal training budget
The opportunity to lead a project, develop project management skills and improve long term career prospects Mentoring by a Knowledge Transfer Network Adviser Full access to university resources to complete the project Access to a full range of continuing professional development modules within the University and bespoke training packages via BicycleTx personal development framework Gain experience in a drug discovery environment Ability to work in a largely self-determined way, across the industry-academic partnership
The KTP Associate will be an employee of Newcastle University but will spend most of their working time at the company’s premises at Granta Park, Great Abington, Cambridge,
CB21 6GS and when required at Newcastle University. Although the contract is fixed term for a duration of 3 years, more than 70% of KTP staff gain wa permanent job offer by their KTP company.
**Bicycle Therapeutics (NASDAQ**: BCYC) is a clinical-stage biopharmaceutical company developing a novel class of medicines. Our pipeline includes Bicycle Toxin Conjugates® as well as fully synthetic Bicycle® systemic immune cell agonists and Bicycle tumour-targeted immune cell agonists (Bicycle TICAs) focused on oncology indications with high unmet medical need. Bicycle is headquartered in Cambridge, UK, and our US operations run out of Lexington, MA.
Culture is key and all Bicycle employees actively embrace and role model our company values:
We are adventurous. We believe it is the way to deliver extraordinary results for our patients.
We are dedicated to our mission. You cannot change the world if you do not have determination.
We are one team. We only succeed when we work together.
For further details about Knowledge Transfer Partnerships please visit the web page at:
Key Tasks On boarding, familiarisation with the company and university Creation of a detailed plan and complete a mini project Protein purification of important outer membrane bacterial proteins Phage display using BicycleTx’s proprietary technology Assay development and implementation (SPR, biochemical assays) Crystallography - protein crystallisation and solving novel target-compound complex structures Disseminate and embed the knowledge within Bicycle to various stakeholders throughout the KTP via reports, presentations, group discussions, workshops and staff training Present findings to stakeholders prepare and complete full documentation Disseminate research via scientific publications and conferences
The Person (Essential)
Knowledge, Skills and Experience Experience in protein biochemistry Experience in structural biology for example X-ray crystallography or cryoEM Experience in a wide range of biochemical and biophysical techniques (E.g., SPR, ITC) Molecular biology relevant to membrane protein expression Experience in membrane protein biochemistry Understanding of peptide structure/activity relationships and early lead optimisation (Desirable) Skills in data analysis statistics and biological mathematics (Desirable) Industrial work experience (Desirable)
Attributes and Behaviour Passion for drug discovery, especially interested in the challenges of antibiotic discovery Ability to be flexible across biological methods and adapt to changes in the project Personal motivation and drive Excellent organisational and planning skills
Thrives in a project environment with ability to work to tight deadlines The ability to work independently and collaboratively with colleagues Strong interpersonal skills with the ability to communicate at all levels to different stakeholder groups in both academia and industry Good attention to detail Is a natural problem solver
Qualifications PhD in Biochemistry or closely related field
Newcastle University is a global University where everyone is treated with dignity and respect. As a University of Sanctuary, we aim to provide a welcoming place of safety for all, offering opportunities to people fleeing violence and persecution.
At Newcastle University we hold a silver Athena Swan award in recognition of our good employment practices for the advancement of gender equality. We also hold a Race Equality Charter Bronze award in recognition of our work towards tackling race inequality in higher education REC. We ar
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