Research Assistant

2 weeks ago

Edinburgh, United Kingdom University of Edinburgh Full time

**Grade UE06 £31,396 - £36,024 per annum. (A revised salary range for this grade of £32,982 - £38,205 is planned to take effect from Spring 2024).**

**College of Medicine & Veterinary Medicine - Edinburgh Cancer Research Centre**

**Full time - 35 hours per week**

**Fixed-Term for 12 months
**The Opportunity**:
We are looking for a Research Assistant to join our team based at IGC (ECRC) for a 2 year post. Our lab studies mutations in the metabolic isocitrate dehydrogenase (IDH1/2) genes and this project focusses on how these mutations re-program liver cells, in the context of biliary cancer. We are using CRISPR-edited human cells and novel transgenic models in mice to examine how these mutations affect the liver’s response to damage and explore the link between injury and metabolic re-programming.

Ideally, the post holder should have some experience of cell culture, tissue processing and will be able to perform laboratory analyses of human and mouse tissue including genotyping, IHC, rt-PCR, western blotting and prepare samples for external providers (transcriptomics, metabolomics). A large proportion of the work will be based on animal experiments; a PIL is a desired but not an essential requirement for the post.

Our lab is highly collaborative and works closely with the group of Dr Luke Boulter. The post holder will undertake independent work on a day-to-day basis but will receive supervision from Rachel Guest and Luke Boulter.

This post is full-time (35 hours per week), however, we are open to considering part-time or flexible working patterns.

**Your skills and attributes for success**:

- A proactive, enthusiastic approach to science
- Ability to work both independently and as part of a team
- Experience of molecular techniques that may include (but not limited to) rt-PCR, IHC, genotyping and sample preparation for external providers
- Experience of tissue processing and cell culture

**Click **here **to view a copy of the full job description (opens new browser tab)**

**As a valued member of our team you can expect**:

- A competitive salary of Grade UE06
- An exciting, positive, creative, challenging and rewarding place to work.
- To be part of a diverse and vibrant international community
- Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our **staff benefits page **(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits

**Championing equality, diversity and inclusion**

The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.

Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our **right to work webpages **(opens new browser tab).

**Key dates to note

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