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Research Assistant
3 months ago
**UE06 £30,619 - £35,308 Per Annum**
**College of Medicine and Veterinary Medicine / MRC Human Genetics Unit (MRC HGU)**
**Full-time, 35 hours per week**
**Fixed-term, 3 years
A 3-year position of Research Assistant (UoE grade 6) is available in the group of Grzegorz Kudla at the MRC Human Genetics Unit (MRC HGU), University of Edinburgh.
**The Opportunity:
The successful applicant will support deep mutational scanning studies of human disease genes, in close collaboration with postdoctoral researchers in the Kudla lab and at the MRC HGU Genome Engineering Facility. The main areas of work will be the construction of plasmids compatible with modern saturation mutagenesis, barcoding, recombineering and genome engineering technologies; construction of mammalian cell lines capable of integrating plasmid libraries via site-directed recombination or CRISPR/Cas9; and large-scale transfection of human cells using the MaxCyte technology. You will use methods available in the lab (gene synthesis, saturation mutagenesis, cell engineering), and introduce new methods as they become available. You will have the opportunity to participate in group and section meetings with experimental and computational scientists to learn new skills in protein, RNA and cell biology.
**Your skills and attributes for success**:
- A BSc in Biomedical Sciences (or similar), and a passion for working in a modern research laboratory
- Experience in molecular/synthetic biology, cell biology and cell culture techniques
- Excellent written and spoken English and good communication skills.
- Enthusiasm and ability to work as part of a team.
- Experience with at least one of the following: saturation mutagenesis, high-throughput studies of variant effects, genome editing, recombination mediated cassette exchange.
**Click to view a copy of the **full job description
**As a valued member of our team you can expect**:
An exciting, positive, creative, challenging and rewarding place to work. We give you support, nurture your talent and reward success. You will benefit from a competitive reward package and a wide range of staff benefits, which includes a generous holiday entitlement, a defined benefits **pension scheme **, **staff discounts, **family friendly initiatives **, flexible working and much more. Access our **staff benefits page **for further information and use our **reward calculator **to find out the total value of pay and benefits provided.
The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.
If invited for interview you will be required to evidence your right to work in the UK. Further information is available on our **right to work **webpages **(opens new browser tab).
The University may be able to sponsor the employment of international workers in this role. This will depend on a number of factors specific to the successful applicant.
