Research Associate

3 weeks ago


South Kensington, United Kingdom Imperial College London Full time

We are looking to appoint a Research Associate to join the Osier laboratory within the Department of Life Sciences at Imperial College London.

**Duties and responsibilities**:
You will be expected to perform the outlined experiments to a high standard. In particular, you will be expected to:

- Establish antibody-dependent cellular cytotoxic) assays for Plasmodium falciparum parasites using Natural Killer Cells
- Optimize the ADCC assays to analyze immune responses to individual recombinant merozoite antigens
- Develop assays to characterize the type, abundance, cellular distribution and polymorphisms of FcY receptors in natural killer cells in autologous samples from study volunteers
- Conduct experiments to determine whether antibodies against specific recombinant antigens raised in mice induce functional antibodies in the ADCC assay

You will also be expected to:

- Acquire, analyse, and interpret research data and results
- Ensure the validity, reliability, and reproducibility of data at all times
- Maintain accurate and complete records of all findings
- Prepare material for presentation in oral and poster formats
- Present findings to colleagues and at conferences
- Assist in the drafting of publications for submission to refereed journals
- Take initiative in the planning of research
- Prioritise tasks within agreed work schedule
- Help train students and others associated with the lab in general scientific approaches and specific experimental techniques
- Contribute to the development of experimental techniques, models, and methods
- Attend relevant workshops and conferences as necessary
- Develop contacts and research collaborations within the College and the wider community
- Help maintain a laboratory environment that is interesting, pleasant, and conducive to high-level experimental work
- Help direct the work of small research teams including undergraduate and postgraduate students
- Take responsibility for organising resources and effective decision making in support of research

**Essential requirements**:
Hold a PhD degree (or equivalent) in Immunology or a related discipline.

You must be able to demonstrate experience in the following areas:

- Molecular techniques (PCR, recombinant protein expression)
- Culturing and performing assays with pathogenic parasites
- Proficiency in cell isolation from PBMCs and phenotyping by Flow cytometry
- Bioinformatic data analysis (desirable)

It is essential that you have:

- The ability to work as part of a team and be open minded and cooperative
- Excellent verbal and written communication skills
- The ability to write clearly and succinctly for publication
- The ability to organise your own work with mínimal supervision and prioritise in response to deadlines

**Further information**:
This is a full time, fixed-term position for one year. You are expected to start from mid-March 2023 (or soon thereafter). You will be based at South Kensington Campus.

**Documents**:

- Job Description Research Associate.pdf


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