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Associate Director
4 months ago
**Associate Director - Analytical Science Automation Design and Control Team**:
**Location**:Macclesfield - UK**
**Competitive Salary & Benefits**
**Date Posted: 19.12.22**
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we’re more than one of the world’s leading pharmaceutical companies At AstraZeneca, we 're proud to have an outstanding workplace culture that encourages innovation and collaboration. Here, employees are empowered to express different perspectives and are made to feel valued, energised and rewarded for their ideas and creativity.
Pharmaceutical Technology and Development (PT&D) is the bridge that turns forward-thinking science into medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devices required to support new medicines - from supplies for use in early toxicology studies and clinical trials to commercial. We also develop and establish robust and reliable commercial manufacturing processes that ensure we can supply life changing medicines to patients across the world.
We are looking for an **Associate Director **to head a new** Analytical Science Automation Design and Control Team** that is being created This Team will be responsible for the delivery of analytical excellence across key Route Design, Process Design and Optimisation deliverables, requiring broad analytical skills and cross discipline working to achieve high quality outcomes.
Specifically, this team will include automation and screening, route design and development of enhanced control strategy and flow chemistry. The creation of this team will bring agility to these areas in both responsivety to current ways of working but more importantly in the development of approaches to build an enhanced digital ecosystem.
**Key Accountabilities**:
In this role, you will:
- Provide leadership and mentoring to a team consisting of 8-10 analytical scientists to ensure analytical excellence in the effective design and development of API route development and control strategies for the whole PR&D portfolio of molecules
- Have technical responsibility for the projects in your team, driving the use of standard process in accordance with the standardised chemical development process within AstraZeneca
- Fiscal oversight to ensure internal and external resourcing is delivered in accordance with governance expectations
- Accountability to drive the introduction of in line analytics where appropriate including the delivery of regulatory guidance to the business for these areas
- Have accountability for building development and improvement strategies to drive the analytical science required to support the team including coaching of business insight within your area
- Work with the team to help them delivery their clear and stretching goals aligned to project deliverables and the strategic priorities of the organisation. Ensure progress against agreed plans and work with TM group and section to assure consistency of approach to individual development
- Work collaboratively with all CD line managers to drive talent development. Use development discussions, coaching and mentoring to accelerate the development of individuals within your team and support opportunities for growth of key talent across the organisation
- Champion using lean tools, standard process and innovative approaches (for example advanced modelling and simulation, digital design) to improve efficiency, facilitate problem solving and improve the sustainability of our developmental portfolio and commercial products
- Ensure all activities comply with AstraZeneca Pharmaceutical Quality System, and SHE standards
- Be a visible role model for the AstraZeneca Values and champion an inclusive culture ensuring individuals are supported to speak up and share their opinions and ideas to help contribute to the overall success of the organisation and create a great working environment.
**Essential Requirements**:
- Significant experience of at line or in line analytics in a development and commercial environment
- Significant relevant post graduate experience working within a Research & Development environment within the pharmaceutical industry with expert knowledge of CMC analytical characterisation/control and technology that provides solutions to drug substance understanding
- A proven track record in the area of Pharmaceutical Quality Systems and cGMP with an understanding of the procedures and controls required to assure patient safety
- A detailed understanding of the drug development process and the product life cycle and how chemical development contributes to it
- Significant experience introducing new analytical technologies to the business
- Significant experience of regulatory authoring of clinical and commercial submissions and com
