Postdoctoral Research Fellow

3 weeks ago

Edinburgh, United Kingdom University of Edinburgh Full time

**UE07 £37,099 to £44,263 per annum (A revised salary range for this grade of £39,347 to £46,974 is planned to take effect from Spring 2024)**

**Centre for Inflammation Research / Institute for Regeneration and Repair**

**Full-Time: 35 hours per week**

**Fixed-Term Contract: 20 months
**The Opportunity**:
The University of Edinburgh is seeking an independent and motivated Postdoctoral fellow to be part of an interdisciplinary team studying skin regeneration in the spiny mouse ( _Seifert A et al., Nature 2012 _). After skin autotomy, the spiny is able to fully regenerate dorsal skin with mínimal fibrotic response. This project will use complementary approaches/models to study the contribution of specific cells and soluble factors to skin regeneration in the spiny, including: microsurgical mouse models, molecular biology and transcriptomics/proteomics.

The project aims to enhance therapeutic approaches for skin regeneration.

Molecular biology techniques (immunohistochemistry, PCR, WB, etc.) including microscopy experience is essential. Experience performing and analysing single cell sequencing, spatial transcriptomics and proteomics data is highly desirable. Experience handling human skin and isolating, characterizing and culturing primary human/mouse cells (2D and 3D) is desirable.

About us: We are a young and enthusiastic ageing-related research group. Our primary focus is to foster great science and imagination, in an environment that is inclusive, inspirational (and fun). The successful applicant will be supported to learn new skills, and to lead projects independently as well as to support our group. We encourage (and support) independent manuscript/grant writing, presentation of data in national/international conferences and attendance to courses that can help with scientific performance/personal development at all levels.

**Your skills and attributes for success**:

- A PhD submitted or examined in cell biology, with relevant post-graduate research experience in skin ageing and regeneration
- Proven track record of independent manuscript writing for publication
- Experience with microscopy and transcriptomics (single cell, spatial) and proteomics (including analysing)
- Experience with murine animals models (ideally surgical models, such as skin transplant) Ability to communicate complex information clearly, orally and in writing.

**Click to view a copy of the full **job description **(opens new browser tab).
**As a valued member of our team you can expect**:

- A competitive salary of £37,099 to £44,263
- An exciting, positive, creative, challenging and rewarding place to work
- To be part of a diverse and vibrant international community
- Comprehensive Staff Benefits, such as a generous holiday entitlement, a defined benefits pension scheme, staff discounts, family-friendly initiatives, and flexible work options. Check out the full list on our **staff benefits page **(opens in a new tab) and use our reward calculator to discover the total value of your pay and benefits

**Championing equality, diversity and inclusion**

The University of Edinburgh holds a Silver Athena SWAN award in recognition of our commitment to advance gender equality in higher education. We are members of the Race Equality Charter and we are also Stonewall Scotland Diversity Champions, actively promoting LGBT equality.

Prior to any employment commencing with the University you will be required to evidence your right to work in the UK. Further information is available on our **right to work webpages **(opens new browser tab).

On this occasion the University will not consider applicants requiring sponsorship for this role. International workers will therefore only be able to take up this role if they can demonstrate an alternative right to work in the UK.

**Key notes for applicants**:
**About the team**:
The Institute for Regeneration and Repair (IRR) is a large multidisciplinary cross-college institute composed of three world-class research centres. Our scientists and clinicians study tissue regeneration and repair to advance human health and reproductive outcomes across two state-of-the-art buildings with capacity for over 1,000 staff and students. The institute provides a fertile and dynamic environment, which allows its researchers and professional services staff to flourish.

**CIR**

The Centre for Inflammation Research (CIR; Director, Professor David Dockrell) leverages peer-reviewed interdisciplinary research programmes and focussed collaboration, to characterise mechanisms of acute and chronic inflammation. The CIR aims to characterise what promotes health at the molecular level in order to prevent the harmful consequences of inflammation in clinical medicine.

Effort is targeted at: inhibiting the initiation of inflammation by blocking specific molecular triggers and by modulating cellular and tissue responses resulting in organ dysfunction; finding new approaches to modulate established inflammatory re

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