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Bioinformatician in Protein Structure and Genetic
3 months ago
**The Imperial jobs site will be temporarily unavailable from 16.00pm Friday 23rd February to 12.00pm Wednesday 28th February as we move to a new Job site platform.**
**Applications started, not yet submitted by 16:00 23rd February will need to be started again on the new platform.**
We are looking to recruit an experienced Bioinformatician with professional experience in software development to work on a Wellcome Trust funded project (i) to develop novel genetic variant and protein modelling algorithms using machine learning and then (ii) to disseminate their use to the community via web-site development.
The project will involve developing novel algorithms, typically using a machine learning strategy, together with the dynamic web interfaces. The project will be supervised by Professor Michael Sternberg and Dr Alessia David at Imperial in collaboration with Professor Richard Houlston FRS at the Institute of Cancer Research (Sutton, London).
You will be a member of the team working in the Centre for Integrative and System Biology and Bioinformatics. The Centre also run a popular master’s course in Bioinformatics and Theoretical System Biology attended by about 20 students every year. You will have the opportunity to help in supervising master’s and undergraduate projects in bioinformatics related to your research.
**Duties and responsibilities**:
You will develop and support the protein and genetic variant modelling resources Missense3D and/or Phyre working on the algorithmic back end and the dynamic web site front end. In addition, you will help in disseminating and supporting the use of these resources. **The post requires professional level experience in coding in a high-level language and, as the major language for software development is Python, we require experience in coding in this language**. **We also require** **a broad knowledge of bioinformatics, including about protein structure.**
**Essential requirements**:
- You must have an undergraduate degree in a biological, physical, numerical or computational discipline
- ** You must have a broad knowledge of Bioinformatics, including about protein structure,** obtained via software development and/or a postgraduate degree in Bioinformatics or a very closely related discipline.
- You must have **extensive experience of coding to a professional level** in a high-level language such as Python or C and in particular experience of coding in
- You must have experience of the Linux operating system.
- In addition, it is desirable that you have (i) previously developed a bioinformatics resource, (ii) have had experience of working on computational studies on protein 3D structure, (iii) have developed algorithms using machine learning and (iv) experience of coding in the development of a dynamic web site using technologies such as HTML, Django, Flask, CSS.
**Further information**:
This is a full time, fixed term position until 30 April 2026 with possibility of extension. You will be based at South Kensington Campus.
As this is a readvertisement, we will not be considering previous applicants except if their skill set has changed substantially.
**Documents**:
- Job Description Bioinformatician.pdf
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