Principal Investigator

2 weeks ago

Birmingham, United Kingdom Tilda Research Inc. Full time

Our Mission

Tilda exists to accelerate the development of new medical treatments by providing every person easy access to clinical trials. As a tech-enabled clinical trial network, we build software and services to help pharma innovators better execute their clinical trial programs. Our work leads to faster cures and thus institutes a meaningful impact on millions of lives. You can help us realize that goal.

Who are we?

Tilda Research is an innovator in clinical research recruitment and trial execution. We operate a growing network of clinical research sites in the US, and our team has worked on over 250 pan-indication Phase I through IV studies. Our founders are successful serial entrepreneurs, with three of their past companies leading to IPOs (VMware, MobileIron) or exits (LexentBio acquired by Roche). We also build software and support clinical trial infrastructure to help pharmaceutical companies identify, enroll, and execute clinical trials efficiently.

Who are you?

We are seeking an experienced Principal Investigator (PI) with an internal or family medicine background to conduct and oversee studies. This role would be the primary PI for Tilda’s Birmingham, Al site. You will be responsible for ensuring the successful execution of research protocols, patient safety, maintaining compliance with regulatory requirements, and contributing to the growth and success of our research site. The position would be part-time to start with the option to expand hours dependent on interest and study demand.

Responsibilities
  • Provide overall medical direction and medical review of protocols in conformance with the investigational plan and good clinical practice.
  • Provide medical and scientific feasibility assessments for all new sponsor inquiries.
  • Ensure that the safety and well-being of all participants in the study at the trial site are p rotected
  • Ensure data collected at the study site is credible and accurate.
  • Ensure the rights, integrity, and confidentiality of all participants in the trial at the site are protected
  • Participate in monitoring visits and sponsor meetings; allow monitoring and auditing by sponsors and inspection by appropriate regulatory agencies.
  • Perform physical assessments and study procedures
  • Review participants' medical history
  • Administer Investigational Product
  • Review and adhere to the study protocol
  • Be thoroughly familiar with the appropriate use of the investigational product (study drug) as described in the protocol and Investigator's brochure/product monograph and other documents provided by the sponsor.
  • Ensure accuracy, completeness, legibility, and timeliness of data reported on the CRF (case report form) and be consistent with source documents.
  • Ensure participants are informed and receive appropriate therapy and follow-up if the trial is prematurely terminated or suspended for any reason.
  • Immediately report Serious Adverse Events (SAEs) or any abnormalities affecting participants' safety to sponsors and the IRB as per specific reporting guidelines
  • Maintain proper documentation
  • Ensure that the study, consent, and other documents provided to the subjects are approved by the IRB and comply with GCP and other regulatory requirements
  • Maintain trial documents specified by the Essential Documents section of the ICH guidelines and as required by applicable regulatory requirements
  • Provide access to research-related records to monitors, auditors, representatives of the IRB, and regulatory authorities
Required:
  • Medical degree (MD or DO) with board certification in Internal Medicine or Family Medicine
  • Active medical license in California
  • Clinical research experience is required with a minimum of 10 completed studies.

$130 - $160 an hour

A bit of info aboutwho we are:

We are a Bio-IT startup based in San Francisco, backed by two of the largest health care institutional investors: 8vc () and Optum / United Health Group (Fortune #5 company). We are an innovator in clinical research execution and work with some of the largest pharma companies to accelerate their medical innovations to market. We are currently in stealth mode and have a limited web presence. We are scaling Series A startup. Our founders are successful serial entrepreneurs, with three of their past companies leading to IPOs (VMware, MobileIron) or exits (LexentBio acquired by Roche).

#J-18808-Ljbffr

  • Senior Consultant – Reactive Investigations

    Found in: Talent UK C2 - 1 week ago

    Birmingham, United Kingdom RSM Full time

    Senior Consultant – Reactive Investigations (12 Month FTC)We are searching for an experienced Senior Consultant – Reactive Investigations (12 Month FTC) Consulting brings together multiple teams across Transactions, Risk & Consulting, ABA, and Outsourcing to provide client-centric solutions for RSM’s current and future clients within the middle market....

  • Principal Technology Engineer

    Found in: Talent UK C2 - 2 weeks ago

    Birmingham, United Kingdom National Highways Full time

    Your New Role  National Highways have an excellent opportunity for a Principal Technology Engineer to join our team in the Midlands region. As a Principal Engineer you will provide technical expertise and leadership in the identification and evaluation of technology asset specific needs and early solutions, while assuring adherence to defined asset...

  • Principal Bridge Engineer FTC

    Found in: Talent UK C2 - 9 hours ago

    Birmingham, United Kingdom Kier Group Full time

    An excellent opportunity is available for a Principal Bridge Engineer to join our Structures team in Kier Design Solutions. This role, based in Birmingham, involves providing engineering services, including scheme investigation, site and structure inspections, data collection and analysis, feasibility studies, preliminary and detailed design, preparation of...

  • Principal Consultant

    Found in: Talent UK C2 - 1 week ago

    Birmingham, United Kingdom RSM Full time

    Principal ConsultantWe are searching for an experienced Principal ConsultantConsulting brings together multiple teams across Transactions, Risk & Consulting, ABA, and Outsourcing to provide client-centric solutions for RSM’s current and future clients within the middle market. Our Consulting team has a major role to play in driving forward the growth of...

  • Assistant Research Practitioner

    10 hours ago

    Birmingham, United Kingdom The Royal Orthopaedic Hospital NHS Foundation Trust Full time

    The post holder will be working across all specialties within the Trust depending of the needs of the service. Post holders will support, and be partly responsible, for relevant studies in their own right subject to training and competency assessments and the delegation of these duties by the respective principal investigators.

  • Principal Engineer – Power Electronics Systems Engineering

    Found in: Appcast UK C C2 - 1 week ago

    Birmingham, United Kingdom Changan UK R&D Centre Limited Full time

    About the RoleChangan is undergoing a major transformation to electrify the powertrains of our passenger car business. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an experienced Principal Engineer – Power Electronics Systems Engineering to...

  • Principal Engineer – Power Electronics Systems Engineering

    Found in: Appcast Linkedin GBL C2 - 1 week ago

    Birmingham, United Kingdom Changan UK R&D Centre Limited Full time

    About the RoleChangan is undergoing a major transformation to electrify the powertrains of our passenger car business. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an experienced Principal Engineer – Power Electronics Systems Engineering to...

  • Principal Engineer – Power Electronics Systems Engineering

    Found in: Talent UK 2A C2 - 1 week ago

    Birmingham, United Kingdom Changan UK R&D Centre Limited Full time

    About the RoleChangan is undergoing a major transformation to electrify the powertrains of our passenger car business. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an experienced Principal Engineer – Power Electronics Systems Engineering to...

  • Principal Engineer – Power Electronics Systems Engineering

    Found in: Appcast UK C2 - 1 week ago

    Birmingham, United Kingdom Changan UK R&D Centre Limited Full time

    About the RoleChangan is undergoing a major transformation to electrify the powertrains of our passenger car business. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an experienced Principal Engineer – Power Electronics Systems Engineering to...

  • Principal Engineer – Power Electronics Systems Engineering

    Found in: Whatjobs ES C2 - 6 days ago

    Birmingham, United Kingdom Changan UK R&D Centre Limited Full time

    About the Role Changan is undergoing a major transformation to electrify the powertrains of our passenger car business. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an experienced Principal Engineer – Power Electronics Systems Engineering to...

  • Power Electronics Systems Engineering- Principal Level

    1 week ago

    Birmingham, United Kingdom European Recruitment Full time

    Principal Engineer – Power Electronics Systems Engineering Permanent/Full Time About the Role Our client is dedicated to powertrain design and development for next generation vehicles. The UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an...

  • Power Electronics Systems Engineering- Principal Level

    Found in: Whatjobs ES C2 - 6 days ago

    Birmingham, United Kingdom European Recruitment Full time

    Principal Engineer – Power Electronics Systems Engineering Permanent/Full Time About the Role Our client is dedicated to powertrain design and development for next generation vehicles. and the UK R&D Centre is at the forefront of this work to develop the future generation of electrified, connected, and intelligent powertrains. We are looking for an...

  • E-Drive Controls Engineer

    Found in: Whatjobs ES C2 - 6 days ago

    Birmingham, United Kingdom European Recruitment Full time

    Senior/Principal E-Drive Controls Engineer Full-time · Mid-Senior level About the job We are looking for an experienced e-drive and power electronics controls engineer to join the client to lead their work in this area. Main Duties and Responsibilities • Lead the development of e-drive and power electronics control systems • Capturing and...

  • Cdm Coordinator

    5 days ago

    Birmingham, United Kingdom Mitie Full time

    Mitie are looking for a CDM Coordinator to join an account-based Projects team providing CDM Management services for Mitie and our diverse client portfolio to achieve compliance with CDM 2015 The role is geographically based, with site visits and team meetings on site as required, the role supports projects managed by the Projects team and will provide...

  • Service Desk Analyst

    Found in: Whatjobs ES C2 - 6 days ago

    Birmingham, United Kingdom Hays Full time

    Hays are looking for a service desk analyst (2nd line support technician) to join a fast-growing SME MSP provider based near Aston. This role is an on-site position working with a good, strong delivery team.You must have skills in the following: Expert in Office 365 & Intune with an ability to learn quickly and support end-user devices to a second-line...

  • Service Desk Analyst

    6 days ago

    Birmingham, United Kingdom Hays Full time

    Hays are looking for a service desk analyst (2nd line support technician) to join a fast-growing SME MSP provider based near Aston. This role is an on-site position working with a good, strong delivery team.You must have skills in the following: Expert in Office 365 & Intune with an ability to learn quickly and support end-user devices to a second-line...

  • HSE Advisor

    1 week ago

    Birmingham, United Kingdom We Manage Jobs(WMJobs) Full time

    The BOA Group is a unique and outstanding creative educational hybrid, committed to the highest standards of excellence.We are a growing Multi-Academy Trust offering creative hubs for the expressive arts and for specialist technical and digital skills. Currently comprising of three academies – ‘BOA Creative, Digital and Performing Arts’ (opened in...

  • Health & Safety Advisor - Remote/ Field

    1 week ago

    Birmingham, United Kingdom Irwin & Colton Limited Full time

    Health and Safety Advisor Irwin and Colton are working with a major Principal Contractor to recruit a site-based Health and Safety Advisor. This role is an excellent opportunity for a proactive and motivated health and safety professional looking to further develop and grow their career with a leader in the construction industry. Responsibilities of the ...

  • Senior/Principal Civil/Structural Engineer

    Found in: beBee S GB - 3 weeks ago

    Birmingham, United Kingdom AtkinsRéalis Full time

    Job DescriptionAtkinsRéalis is looking for a Senior Civil / Structural Engineer to join the Design and Advanced Technology (D&AT) Practice, to work on projects based principally in our Birmingham office but with opportunities to work at our own and our Client locations elsewhere in the UK and overseas. You will be able to work on a range of projects from...

  • Senior/Principal Civil/Structural Engineer

    Found in: Talent UK C2 - 1 week ago

    Birmingham, United Kingdom SNC-Lavalin Full time

    Job Description AtkinsRéalis is looking for a Senior Civil / Structural Engineer to join the Design and Advanced Technology (D&AT) Practice, to work on projects based principally in our Birmingham office but with opportunities to work at our own and our Client locations elsewhere in the UK and overseas. You will be able to work on a range of...