Senior Scientist

4 weeks ago

Stevenage Hertfordshire, United Kingdom GlaxoSmithKline Full time

A new Senior Scientist position has come up in the Analytical Development Department at our Stevenage, UK site. The purpose of this role is to plan, design and execute work/experimental programmes to further the course of oligonucleotide discovery and development projects and programmes to reach project milestones.
The successful candidate will have extensive expertise in mass spectrometry (LC-MS, LC-MS/MS and GC-MS) as applied to oligonucleotide analysis. and their application to oligonucleotide analysis would be preferred.
We offer a competitive salary, an annual bonus based on company performance, healthcare and wellbeing programmes, pension plan membership, and shares and savings programme.
our Performance with Choice programme offers a hybrid working model, empowering you to find the optimal balance between remote and in-office work.
Plan, design and execute experimental programmes to further the course of oligonucleotide discovery and development projects / programmes and enable key outcomes, in particular using mass spectrometry expertise (LC-MS, LC-MS/MS and GC-MS).
propose solutions and strategies with team members and more senior staff.
Contribute to regulatory dossiers and author/review expert reports.
Comply with the requirements of quality, safety and GSK policies and procedures.
PhD, preferably in a mass spectrometry related discipline, or BSc with experience in the pharmaceutical industry
Q-Tof, Orbitrap) in order to provide key information for projects at all stages of pharmaceutical development, from early phase development to marketed product support, especially for oligonucleotide development
Proven track record of development of novel LC-MS and GC-MS methodology in the pharmaceutical or related industry
CD, UV, vibrational) and their use to enable understanding of the drug manufacturability, comparability and performance (e.g. diastereoisomer ratios, higher order structure (HOS))
Experience optimising and/or developing chromatographic and instrument methods for both qualitative and quantitative analysis of oligonucleotides
Knowledge of oligonucleotide chemistry. Knowledge of ICH guidelines, experience in regulated GxP laboratory, familiarity with regulatory submission documents
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We’re uniting science, technology and talent to get ahead of disease together.
Why GSK?
Uniting science, technology and talent to get ahead of disease together.
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).
While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. This ensures that all qualified applicants will receive equal consideration for employment without regard to neurodiversity, race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).
We believe in an agile working culture for all our roles. recruitment@gsk.We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.
Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting For the Record site.
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