Research And Development Manager

3 weeks ago

London, United Kingdom Square One Pharma Full time
Job Description

Cell Line Development Lead

You'll lead cell line development program based in London, focusing on the advancement and improving of cell lines. Collaborating closely with experts in stem cell biology, computational biology, and bioprocess engineering, you'll be instrumental in shaping the future of the company.


As the technical lead in Cell Line Development team, you'll take charge of isolating, engineering, and validating new adipogenic cell lines. Guiding a dedicated and skilled team, your responsibilities will centre on devising and implementing automated workflows for mammalian stem cell engineering.


Key qualifications:

  • A PhD (or equivalent industry experience) in molecular biology, synthetic biology, mammalian stem cell biology, or a related field.
  • Minimum two years' experience in mammalian cell line development and genome engineering, preferably in a commercial setting.
  • Strong expertise in molecular biology techniques, cell line engineering tools, molecular cloning, and genetic construct design.
  • Proficiency in genome editing techniques, particularly using CRISPR/Cas9 and associated methodologies.
  • Experience optimising transfection and transduction.
  • Proven ability in managing projects and coordinating workflows involving cell line development and molecular biology
  • Willingness to actively engage in laboratory work, dedicating at least half of your time to molecular biology and cell culture activities.
  • Possess enthusiasm, inquisitiveness, and a proactive attitude.
  • Excellent team player.


Ideally you'll have experience in some, but not necessarily all, of the following areas:

  • High-throughput screening using image-based techniques and flow cytometry.
  • Single-cell cloning and candidate selection from screening in adherent and suspension culture, incorporating high-throughput and automated liquid handling tools
  • Target validation including phenotypic and functional assays
  • Analysis of qPCR, NGS/WGS and RNAseq data (bulk and single-cell samples)
  • Understanding of GMP (or equivalent) regulations concerning cell line development
  • Mesenchymal stem/stromal cell culture and differentiation

  • Research Manager[976171]

    5 days ago

    London, United Kingdom BMG Research Full time

    Our clients include the largest government departments, such as Defra, the Department for Business and Trade, the Department for Energy Security and Net Zero, HMRC, the Home Office and the Department for Education. We also work with government agencies and regulators, local authorities, charities, utility companies and housing associations. Our projects...

  • Senior Research Manager

    19 hours ago

    London, United Kingdom IFF Research Full time

    We have a number of opportunities across our teams for experienced Senior Research Managers.You MUST have current UK social market research experience.You must have experience that is relevant to our positions and be able to demonstrate skills that align with the social research sector and our clients.Who is IFF?We're an award-winning social and market...

  • Senior Research Manager

    9 hours ago

    Greater London, United Kingdom IFF Research Full time

    We have a number of opportunities across our teams for experienced Senior Research Managers. You MUST have current UK social market research experience. You must have experience that is relevant to our positions and be able to demonstrate skills that align with the social research sector and our clients.Who is IFF? We're an award-winning social and market...

  • Senior Research Manager

    3 hours ago

    Greater London, United Kingdom IFF Research Full time

    We have a number of opportunities across our teams for experienced Senior Research Managers. You MUST have current UK social market research experience. You must have experience that is relevant to our positions and be able to demonstrate skills that align with the social research sector and our clients.Who is IFF? We're an award-winning social and market...

  • Research Manager

    1 month ago

    London, United Kingdom MMR Research Worldwide LTD Full time

    Are you a researcher looking for an exciting next step in your career? Do you enjoy working on high profile global accounts within the FMCG industry?We are looking for an energetic, self-motivated and passionate individual to join our brilliant London research team as a Research Manager. CompanyMMR is an independent, global company specialising in food,...

  • Research Manager Food

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK.Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Research Manager Food

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    Job DescriptionWe are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK.Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our...

  • Sensory Qualitative Research Manager

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    5 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK. Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Sensory Qualitative Research Manager

    4 days ago

    London, United Kingdom MMR Research Full time

    We are currently looking for a dynamic sensory scientist or R&D professional to work as a Qualitative Sensory Research Manager on exciting client innovation projects in London, UK.Within this role, you will be working on all the portfolio of Sensory Qual methodologies we have developed at MMR for the last 12 years. You will be supporting our clients in...

  • Quantitative Researcher

    1 month ago

    London, Greater London, United Kingdom G-Research Full time

    Do you want to tackle the biggest questions in finance with near infinite compute power at your fingertips?G-Research is a leading quantitative research and technology firm, with offices in London and Dallas. We are proud to employ some of the best people in their field and to nurture their talent in a dynamic, flexible and highly stimulating culture where...

  • Head of Manager Research

    5 days ago

    Twickenham, Greater London, United Kingdom NIHR (National Institute for Health and Care Research) Full time €45,700

    The National Institute for Health and Care Research (NIHR) is funded by the Department of Health and Social Care (DHSC). We work in partnership with the NHS, universities, local government, other research funders, patients, and the public. The NIHR funds, enables, and delivers world-leading health and social care research that improves people's health and...