Director of Genome Analytics

4 days ago


Oxford, United Kingdom Ellison Institute, LLC Full time
About EIT:

The Ellison Institute of Technology (EIT) Oxford tackles humanity’s greatest challenges by turning science and technology into impactful global solutions. Focused on areas like health, food security, sustainable agriculture, climate change, clean energy, and AI-driven government innovation, EIT Oxford blends groundbreaking research with practical applications to deliver lasting results.

A cornerstone of EIT Oxford’s mission is its upcoming 300,000-square-foot research facility at the Oxford Science Park, set to open in 2027. This cutting-edge campus will feature advanced labs, an oncology and preventative care clinic, and collaborative spaces to strengthen its partnership with the University of Oxford. It will also host the Ellison Scholars, driving innovation for societal benefit.

The Pathogen Mission highlights EIT’s transformative approach, using Whole Genome Sequencing (WGS) and Oracle’s cloud technology to create a global pathogen metagenomics system. This initiative aims to improve diagnostics, provide early epidemic warnings, and guide treatments by profiling antimicrobial resistance. The goal is to deliver certified diagnostic tools for widespread use in labs, hospitals, and public health.

EIT Oxford fosters a culture of collaboration, innovation, and resilience, valuing diverse expertise to drive sustainable solutions to humanity’s enduring challenges.

EIT is looking to recruit a Director of Genome Analytics to lead computational and statistical analyses of genomic data, focusing on pathogen and human genomics. Reporting to the Principal Scientist, this role is essential to advancing tools and methodologies that address challenges in individual-level diagnosis and population health, particularly for emerging pathogens.

Key Responsibilities:
  • Develop, benchmark, and maintain tools for data quality control, harmonization, and advanced genomic analyses, including technologies such as kmer analysis, de Bruijn graphs, and statistical modeling for epidemiology.
  • Identify and address gaps in existing capabilities, driving innovations to improve performance and introduce transformative advancements.
  • Deliver high-quality scientific code to the Technology Team for integration into regulatory-compliant products.
  • Collaborate with the EIT AI team to implement innovative programs that align with the Pathogen Mission’s objectives.
  • Lead the development of peer-reviewed publications and benchmarking studies to validate advancements in genomic tools.
  • Represent the organization at international conferences, showcasing leadership in genomic science.
  • Recruit, mentor, and manage a team of scientists and developers to achieve program objectives.
  • Collaborate with the Senior Leadership Team to shape and deliver the Pathogen Mission’s strategic goals.
Qualifications & Experience:
  • Proven track record of developing innovative computational methods for population-scale genomic data, evidenced by academic publications or software contributions.
  • Expertise in quality control, manipulation, and analysis of large genomic datasets, with experience resolving data standardization challenges.
  • Leadership experience managing teams of scientific developers using best practices such as agile development, version control, and collaborative coding.
  • Demonstrated ability to design and benchmark computational tools, including statistical power considerations.
  • Experience working with academic and industry partners to accelerate research programs.
  • Strong project management skills, with a proven ability to deliver complex projects on time and within budget.
Desirable Skills:
  • Experience with whole-genome sequencing data in microbiology applications.
  • Familiarity with Oxford Nanopore sequencing technology.
  • Knowledge of epidemiological modeling or genome association studies.

Terms of Appointment:
  • You must have the right to work permanently in the UK with a willingness to travel as necessary.
  • You will live in, or within easy commuting distance of, Oxford.
  • During peak periods, some longer hours may be required and some working across multiple time zones due to the global nature of the programme.

Why work for EIT:
At the Ellison Institute, we believe a collaborative, inclusive team is key to our success. We are building a supportive environment where creative risks are encouraged, and everyone feels heard. Valuing emotional intelligence, empathy, respect, and resilience, we encourage people to be curious and to have a shared commitment to excellence. Join us and make an impact

We offer the following salary and benefits:
  • Salary: £110k-£150k (depending on experience) + bonus + travel allowance
  • Enhanced holiday pay
  • Pension
  • Life Assurance
  • Income Protection
  • Private Medical Insurance
  • Hospital Cash Plan
  • Therapy Services
  • Perk Box
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