Reagent Production and Cell Culture manager
1 month ago
Job summary
Do you want a role safeguarding standards of animal and plant health and welfare?
If so, we would love to hear from you�
The Animal and Plant Health Agency (APHA) is an executive agency of the Department for Environment, Food & Rural Affairs, and works on behalf of the Scottish Government and Welsh Government. Our diverse teams of over 3,000 skilled and committed professionals come together to provide research, advice and support to UK Government for safeguarding animal, public and plant health for benefit of the environment and economy.
The Science Directorate (SD) delivers high quality, high impact and highly relevant multidisciplinary science. Our People are diverse, talented, engaged and inspired to deliver innovative outcomes.
This post supports the work of both the Reagent Production Unit (RPU) and Cell and Tissue Culture Unit (CTC).
In RPU, the role is to maintain supply and production of a wide range of immunological reagents including, antibodies, antigens and kits for use in APHA laboratories and for commercial sale. To assist with test validation and troubleshooting reagents.
In CTC, the job holder will be involved with the preparation of cell cultures and immunological reagents in support of surveillance, research and disease response at APHA and for commercial customers. The main part of the job will be the preparation of primary cell cultures from a variety of animal tissues, this will involve dissection of animal organs and occasional attendance at animal postmortem.
Job description
To manage reagent production in RPU4 ensuring stocks of reagents are maintained, are fit-for-purpose and of high quality, initiating production and testing when new stock is required. Ensure the ISO9001:2015 quality system is supported with production records, datasheets and test summaries and associated documents maintained.
To ensure that reagent orders for the RPU4 workgroup are supplied using the stock management system (Integra), meeting the agreed turnaround times for internal and external orders. Dealing with enquires, complaints and non-conformance issues related to reagent products.
To assist in the validation of new diagnostic assays produced by commercial companies and in-house tests, assisting in the organisation and completion of practical work specific to test validation projects.
To assist in the completion of ad-hoc project work and to assist in trouble shooting tests.
Maintain the smooth running of the laboratory, ensuring room officer duties are completed and managing the equipment servicing and calibration on behalf of the unit.
To maintain a safe working environment in accordance with local safety standards and COSHH regulations, including the regular review of risk assessments and standard operating procedures.
Procurement of laboratory supplies using Oracle SOP.
Functional management of AO staff.
To work flexibly within Biotechnology and Lab Testing if required to ensure continuity of work.��
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Cell and Tissue Culture � Laboratory Manager
Production of primary cell cultures from a variety of animal tissues, this will involve dissection of animal organs and occasional attendance at animal postmortem.
Production of chick/embryo primary cultures.
Production of a variety of established cell lines and associated media.
Routine monitoring of cell cultures for infection with mycoplasma, bacteria and fungi.
Knowledge of animal anatomy and dissection skills desirable but training will be given.
The maintenance of manual and computerised records in accordance with ISO 9001:2015.
To participate in the maintenance of the laboratory and its equipment such as routine cleaning and ensuring equipment is serviced and calibrated.��
Person specification
Experience and skills:
You will need to demonstrate the following:
You will require manual dexterity to carry out dissection of animal organs.Good planning, management skills and experience in a laboratory setting are required to ensure reagents are produced to meet tight deadlines. A working knowledge of immunoassays is desirable.The ability to multi-task and to have a flexible approach to work and be able to cope with change.Must be enthusiastic and self-motivated, able to take responsibility for their own work.Be able to work as part of a team with good interpersonal skills and be able to communicate effectively with others.�Technical ability
You will require manual dexterity to carry out dissection of animal organs.Qualifications
Degree in science subject, or suitable career experience.
Ways of Working
This post requires you to be working in the Laboratory five days per week or less if part-time.
The successful candidate will need to comply with a number of health protocols and wear protective clothing and Respiratory Personal Protective Equipment (RPPE) as required. The work of the post can be physically demanding.
Depending on the areas of work involved you will be expected to have any necessary vaccinations or health surveillance. This will be arranged by the Health Team, Weybridge. It may also be necessary to undergo a pre-employment medical assessment.
Due to access requirements to bio secure areas, individuals must be physically able.
Out of hours work may be required in the event of an incident.� The post will also require Health clearance.
Behaviours
We'll assess you against these behaviours during the selection process:
Working TogetherMaking Effective DecisionsManaging a Quality ServiceTechnical skills
We'll assess you against these technical skills during the selection process:
You will require manual dexterity to carry out dissection of animal organs.Benefits
Alongside your salary of �30,827, Animal and Plant Health Agency contributes �8,323 towards you being a member of the Civil Service Defined Benefit Pension scheme.In return for your dedication and hard work, we will support your ongoing personal development through appropriate training as inclusion, support and the development of our people matter to us. We aim to support the career and personal wellbeing of everyone in APHA.� Our benefits include generous annual leave, a generous employer contributory pension (27%), staff bonuses and recognition, salary sacrifice benefit options, and an employee discount scheme, reward vouchers and in-year bonuses. We also offer additional days off if accrued extra hours (flexi-time �if accumulated), three paid volunteering day per year. We also have a social committee who run team building and fun events at the Weybridge site.�
Everyone in APHA is supported to develop their skills and capabilities. When you join the Directorate, you will be welcomed into your new team through an induction programme that will provide you with helpful information on the civil service, our work and our policies. Your line manager will also work with you to establish your priorities for the year, developing a performance, learning and development plan tailored to you and your role.�
Further details can be found in the Candidate Information Pack.
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