Senior Technical Officer-Process Development

4 weeks ago


London, Greater London, United Kingdom King's College London Full time
Job description

Role purpose

The KCL Centre for Gene Therapy & Regenerative Medicine (CGTRM) in collaboration with the KCL Gene Therapy Vector Facility (GTVF) develops and manufactures ATMPs for a wide variety of novel gene and cell therapies for the treatment of cancers to rare diseases. This is an exciting opportunity to work within one of the largest academic GMP facilities in Europe focusing on the delivery of gene therapy products for early phase clinical trials.

In 2021, MRC/LifeArc/BBSRC announced the establishment of this Gene Therapy Innovation Hub. One of the main points of focus in the innovation component of the Hub will be the further development of new cell lines and vectors for the GMP compliant manufacture of viral vectors for the treatment of a host of acquired and inherited genetic disorders. The appointee will report to the Head of Process Development/Senior Research Fellow.

Role profile

This role is for a qualified and experienced Scientist who has been working in an academic or commercial research laboratory/company related to the development, manufacturing and purifying viral vectors (lenti, retroviral) or other gene therapy products as IMPs.

You will help deliver technical innovation and lead specified work packages, developing the experimental plan with the Head of Process Development and allocating resources. You must have a strong background/knowledge of viral vectors and purification methods and have excellent interpersonal skills to work within and across diverse teams.

Additional experience in associated technologies, such as the use of bio-reactors and concentration technologies for the production of viral vectors are essential.

This post will be offered on a fixed-term contract until 30th Sept 2026 in the first instance.

This is a full-time post - 100% full time equivalent.


Closing date: 22nd April 2024

£43,205 to £45,521 per annum, including London Weighting Allowance.



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