Laboratory Research Scientist

3 weeks ago

London, Greater London, United Kingdom The Francis Crick Institute Full time

Location: The Francis Crick Institute, Midland Road, London

Contract: Fixed term for 2 years, Full time

Short summary

We are seeking an enthusiastic and proactive Laboratory Research Scientist to join a world-leading laboratory working on the sensing and signalling of oxygen levels in cells. The work has broad relevance in biology and direct relevance to many or most human diseases, including heart and lung disease, stroke and cancer. The laboratory is 'problem-based' and deploys a very wide range of technologies to address these problems. Further information can be found about the group at

Key Responsibilities

These include but are not limited to:

  • Provision of technical and research support in the area of hypoxic cell biology including the tissue culture of relevant specialised cells
  • Preparation and analysis of samples for proteomic mass spectrometry (MS), including discovery and targeted MS analyses
  • Contribute to the development of assays of oxygen sensitivity in cultured cells including fluorescence microscopy
  • Performance of cell engineering under the direction and supervision of senior laboratory staff
  • Compliance with all regulatory and safety protocols
  • Accurate organisation of work and experimental record keeping

Experience and Competencies

The post holder should embody and demonstrate our core Crick values:

Bold; Open; Collegial

Essential

  • BSc or MSc in biochemistry, cell biology or related discipline
  • Good working knowledge of general molecular biology techniques including tissue culture
  • Ability to work accurately and maintain good records
  • Strong collaborative ability and teamwork experience

Desirable

  • Experience in protein mass spectrometry
  • Experience in genetic engineering of cells
  • Experience in fluorescence microscopy

About us

The Francis Crick Institute is a biomedical discovery institute dedicated to understanding the fundamental biology underlying health and disease. Its work is helping to understand why disease develops and to translate discoveries into new ways to prevent, diagnose and treat illnesses such as cancer, heart disease, stroke, infections, and neurodegenerative diseases.

An independent organisation, its founding partners are the Medical Research Council (MRC), Cancer Research UK, Wellcome, UCL (University College London), Imperial College London and King's College London.

The Crick was formed in 2015, and in 2016 it moved into a new state-of-the-art building in central London which brings together 1500 scientists and support staff working collaboratively across disciplines, making it the biggest biomedical research facility under in one building in Europe.

The Francis Crick Institute will be world-class with a strong national role. Its distinctive vision for excellence includes commitments to collaboration; developing emerging talent and exporting it the rest of the UK; public engagement; and helping turn discoveries into treatments as quickly as possible to improve lives and strengthen the economy.

  • If you are interested in applying for this role, please apply via our website.
  • The closing date for applications is 19 May 2024.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.

From £31,675 per annum with benefits, subject to skills and experience

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