PhD Studentship: Developing New Chelate Scaffolds for Binding Radiofluorine and Radiometals – Towards Combined Theragnostic Agents for Imaging and Therapy in Medicine

Found in: beBee jobs GB - 2 weeks ago


Southampton, Southampton, United Kingdom University of Southampton Full time

Supervisory Team: Professor Gill Reid & Dr Richard Knoghton

Project Description:

Developing new chelate scaffolds for binding radiofluorine and radiometals – towards combined theragnostic agents for imaging and therapy in medicine

Applications are invited from suitably qualified and motivated candidates for an EPSRC CASE PhD studentship based in Chemistry at the University of Southampton, in collaboration with partners at GE Healthcare. The project focusses on development of new metal complexes for radiofluorination for potential applications as next generation medical imaging agents via positron emission tomography (PET) – an important and widely used medical imaging technique used in hospitals and clinics for detection of diseases such as cancers.

This project is at the coordination chemistry/radiochemistry interface and the successful applicant will have the opportunity to develop skills in the synthesis and characterisation of metal fluoride complexes with macrocyclic co-ligands as possible PET tracer candidates, as well as to use GE Healthcare's facilities at St Thomas' Hospital (London) to develop efficient methods for their radiofluorination (with the fluorine-18 isotope), purification and stability testing. The potential of the compounds for incorporating radiometals will also be explored.

The successful candidate will join a well-established research activity in Chemistry at Southampton and will have access to state-of-the art facilities for the synthesis and characterisation of inorganic coordination complexes. Applicants should hold or be about to hold a 1st class or 2:1 degree in Chemistry or a closely related subject and have a keen interest in both the synthetic and radiochemical aspects of the project. Research experience in molecular inorganic chemistry/coordination chemistry and inert atmosphere techniques would be advantageous.

Full funding for this project is available for 42 months, sponsored by EPSRC and GE Healthcare. Please note that due to funding restrictions this position is open to UK candidates only. The student will be supervised by Professor Gill Reid and Dr Richard Knighton.

If you wish to discuss any details of the project informally, please contact Professor Gill Reid, Email:

Entry Requirements

A very good undergraduate degree (at least a UK 2:1 honours degree, or its international equivalent).

Closing Date: 31 August 2024. Applications will be considered in the order that they are received, the position will be considered filled when a suitable candidate has been identified.

Funding: We offer a range of funding opportunities including Bursaries and Scholarships. For more information please visit PhD Scholarships | Doctoral College | University of Southampton. Funding will be awarded on a rolling basis, so apply early for the best opportunity to be considered.

How To Apply

Apply online: HERE Select programme type (Research), 2024/25, Faculty of Engineering and Physical Sciences, next page select "PhD Chemistry (Full time)". In Section 2 of the application form you should insert the name of the supervisor Prof Gill Reid.

Applications should include:

Research Proposal

Curriculum Vitae

Two reference letters

Degree Transcripts/Certificates to date

For further information please contact: feps-pgr-

We offer a range of funding opportunities including Bursaries and Scholarships



  • Southampton, Southampton, United Kingdom University of Southampton Full time

    Project title: PhD Studentship in Nanophotonics and Metamaterials: Development of Switchable and Programmable Metasurfaces using Novel Materials Supervisory Team: Prof. Otto Muskens; Dr Ioannis ZeimpekisProject description:Metaoptics, the application of metasurface concepts in optical systems, is a rapidly growing field that has the potential to...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Thomas BlumensathSupervisory Team: Thomas Blumensath (ISVR), Daniel Clark (ECS), Mark Mavrogordato (Engineering)Project descriptionX-ray computed tomography uses X-ray radiation to generate three dimensional images of an object's external and internal structure. The method is not only used for medical diagnostics but is also increasingly used...

  • PhD Studentship: Disrupting Oral Biofilm Formation

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and National Biofilms Innovation Centre), Prof. Paul Stoodley (University of Southampton), Dr Rob Howlin (Haleon, industry), Dr David Bradshaw and Dr Ricarda Hawkins (Haleon, industry) Project Description:A fully-funded 4 year National Biofilms Innovation...

  • PhD Studentship

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Benjamin CameronProject descriptionThis PhD is focussed on a new theoretical/computational method to measure material properties in places where they are really difficult to measure: e.g. in a shock wave, in a shear band, or at a crack tip. These are all of critical importance in many engineering problems such as car crashes, manufacturing...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Thomas Blumensath (ISVR), Alex Dickinson (Engineering Sciences) Project descriptionThree dimensional images of the foot taken under loading conditions can provide a valuable clinical tool for the assessment of bone alignment related complaints. However, as these images have to be taken whilst a person is standing, specialised scanners are...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Dr Seung Lee Supervisory Team: Dr Seung Lee (School of Chemistry), Prof. Jeremy Webb (School of Biological Sciences and national Biofilms Innovation Centre), Prof. Paul Stoodley (University of Southampton and Ohio State University)Project description:A fully-funded 4 year PhD studentship (Institute for Life Sciences studentship) for research...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Jonathan GeorgePhD Supervisor: Jonathan GeorgeProject description:The School of Chemistry is offering a fully funded PhD studentship to a highly motivated candidate to start in September 2024. The student will carry out their doctoral research in the George Group, which has recently moved to the University of Southampton.BackgroundThe use...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Chris-Kriton Skylaris (90%) Andrea Russell (10%)Project description:Proton-exchange Membrane (PEM) hydrogen fuel cells are an emerging technology for environmentally sustainable transport and other carbon-neutral energy applications. A crucial component of these devices are the metallic catalyst nanoparticles which allow the chemical...

  • PhD Studentship: Magnetic Resonance Spectroscopy

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Prof Ilya Kuprov, Dr Marina CarravettaProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and commercial skills.Magnetic resonance spectroscopy and...

  • PhD Studentship: Quantum Control of Magnetic Processes

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Project title: Quantum control of magnetic processes Supervisory Team: Prof Ilya Kuprov, Dr Marina CarravettaProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Ivo PetersSupervisory Team: Ivo Peters, Tim WatersProject description:The increasing use of drones and electric bikes offers exciting new opportunities for bespoke and efficient transportation of medical products. This is particularly beneficial for transporting emergency medication quickly or where medicines or patient samples have a shelf...

  • PhD Studentship: Momentum-State Quantum Computer

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Dr Tim FreegardeSupervisory Team: Dr Tim FreegardeProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and commercial skills.The interactions between cold...

  • PhD Studentship: Quantum Nanomaterials Revolution

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Dr Nema AbdelazimSupervisory Team: Dr Nema AbdelazimProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and commercial skills.We are offering an exciting...

  • PhD Studentship

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Professor Pedro Rivera and Dr Ben CameronProject description:Rail safety is dependent upon the ability to control the nucleation and growth of cracks. Current popular techniques focus on crack prevention, e.g. through grinding, but the mechanisms leading to failure remain largely ununderstood. The topic has recently been reviewed...

  • PhD Studentship

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Dr N.C. Townsend, Prof D.A. Hudson and Dr J.A. Bowker (industrial)Project descriptionWave energy can be used to improve the performance of ships and boats. By exploiting hydrodynamically the available wave energy, the motions, emissions, and powering requirements of ships operating in adverse weather conditions can be significantly...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Prof Ilya Kuprov, Dr Marina CarravettaProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive substantial training in scientific, technical, and commercial skills.Spin is a relativistic property of...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Prof Malcolm Levitt FRS, Dr Marina Carravetta, Prof Ilya KuprovSupervisory Team: Prof Malcolm Levitt FRS, Dr Marina Carravetta, Prof Ilya KuprovProject description: The University of Southampton is expanding its PhD research in the area of Quantum Technology Engineering. In addition to the research project outlined below you will receive...

  • PhD Studentship

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Ioannis ZeimpekisProject description:Revolutionising the semiconductor industry with next generation 2D materials and devices.Moore's Law is currently being challenged with Nvidia CEO recently claiming it is over. The scaling of transistors cannot continue due to physical limitations of silicon posing a threat to the sustainable evolution...

  • PhD Studentship

    Found in: beBee jobs GB - 2 weeks ago


    Southampton, Southampton, United Kingdom University of Southampton Full time

    Supervisory Team: Dr N.C. Townsend, Prof D.A. Hudson and Dr J.A. Bowker (industrial)Project descriptionShip model testing is expensive and time consuming. Can we derive hydrodynamic seakeeping and manoeuvring characteristics with focused datasets, eliminating time consuming single variable investigations?In this PhD program you will develop and test novel...


  • Southampton, Southampton, United Kingdom University of Southampton Full time

    PhD Supervisor: Dr Lei LiSupervisory Team: Dr Lei Li, Prof. Age ChapmanProject description:In this unique PhD project, we aim to develop advanced AI models for creating cardiac digital twins, i.e., virtual heart models. We will employ the dataset (imaging, ECG, electronic medical records, etc) collected from the patients, to accurately modelling the anatomy...